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10.1038/srep21749

http://scihub22266oqcxt.onion/10.1038/srep21749
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C4766475!4766475!26912108
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suck abstract from ncbi


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pmid26912108      Sci+Rep 2016 ; 6 (ä): ä
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  • Universal structures of normal and pathological heart rate variability #MMPMID26912108
  • Gañán-Calvo AM; Fajardo-López J
  • Sci Rep 2016[]; 6 (ä): ä PMID26912108show ga
  • The circulatory system of living organisms is an autonomous mechanical system softly tuned with the respiratory system, and both developed by evolution as a response to the complex oxygen demand patterns associated with motion. Circulatory health is rooted in adaptability, which entails an inherent variability. Here, we show that a generalized N-dimensional normalized graph representing heart rate variability reveals two universal arrhythmic patterns as specific signatures of health one reflects cardiac adaptability, and the other the cardiac-respiratory rate tuning. In addition, we identify at least three universal arrhythmic profiles whose presences raise in proportional detriment of the two healthy ones in pathological conditions (myocardial infarction; heart failure; and recovery from sudden death). The presence of the identified universal arrhythmic structures together with the position of the centre of mass of the heart rate variability graph provide a unique quantitative assessment of the health-pathology gradient.
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