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10.1016/j.hpb.2015.07.003

http://scihub22266oqcxt.onion/10.1016/j.hpb.2015.07.003
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suck abstract from ncbi


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pmid26776851
      HPB+(Oxford) 2016 ; 18 (1 ): 49-56
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  • Diagnostic strategy and timing of intervention in infected necrotizing pancreatitis: an international expert survey and case vignette study #MMPMID26776851
  • van Grinsven J ; van Brunschot S ; Bakker OJ ; Bollen TL ; Boermeester MA ; Bruno MJ ; Dejong CH ; Dijkgraaf MG ; van Eijck CH ; Fockens P ; van Goor H ; Gooszen HG ; Horvath KD ; van Lienden KP ; van Santvoort HC ; Besselink MG
  • HPB (Oxford) 2016[Jan]; 18 (1 ): 49-56 PMID26776851 show ga
  • BACKGROUND: The optimal diagnostic strategy and timing of intervention in infected necrotizing pancreatitis is subject to debate. We performed a survey on these topics amongst a group of international expert pancreatologists. METHODS: An online survey including case vignettes was sent to 118 international pancreatologists. We evaluated the use and timing of fine needle aspiration (FNA), antibiotics, catheter drainage and (minimally invasive) necrosectomy. RESULTS: The response rate was 74% (N = 87). None of the respondents use FNA routinely, 85% selectively and 15% never. Most respondents (87%) use a step-up approach in patients with infected necrosis. Walled-off necrosis (WON) is considered a prerequisite for endoscopic drainage and percutaneous drainage by 66% and 12%, respectively. After diagnosing infected necrosis, 55% routinely postpone invasive interventions, whereas 45% proceed immediately to intervention. Lack of consensus about timing of intervention was apparent on day 14 with proven infected necrosis (58% intervention vs. 42% non-invasive) as well as on day 20 with only clinically suspected infected necrosis (59% intervention vs. 41% non-invasive). DISCUSSION: The step-up approach is the preferred treatment strategy in infected necrotizing pancreatitis amongst expert pancreatologists. There is no uniformity regarding the use of FNA and timing of intervention in the first 2-3 weeks of infected necrotizing pancreatitis.
  • |*Drainage/adverse effects/trends [MESH]
  • |*Pancreatectomy/adverse effects/trends [MESH]
  • |*Practice Patterns, Physicians'/trends [MESH]
  • |*Time-to-Treatment/trends [MESH]
  • |Anti-Bacterial Agents/*administration & dosage [MESH]
  • |Biopsy, Fine-Needle [MESH]
  • |Consensus [MESH]
  • |Drug Administration Schedule [MESH]
  • |Health Care Surveys [MESH]
  • |Humans [MESH]
  • |International Cooperation [MESH]
  • |Pancreatitis, Acute Necrotizing/*diagnosis/microbiology/*therapy [MESH]
  • |Predictive Value of Tests [MESH]
  • |Risk Factors [MESH]
  • |Surveys and Questionnaires [MESH]


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