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10.4254/wjh.v8.i6.322 http://scihub22266oqcxt.onion/10.4254/wjh.v8.i6.322 C4766260!4766260!26962398     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       World+J+Hepatol 2016 ; 8 (6): 322-30 Nephropedia Template TP {{tp|p=26962398|t=2016. Burn injury induces histopathological changes and cell proliferation in liver of rats |pdf=|usr=}}{{26962398}} gab.com Text Burn injury induces histopathological changes and cell proliferation in liver of rats JO: World J Hepatol http://www.kidney.de/pget.php?&tw=1&pmid=26962398 #FOAvip AIM: To investigate effects of severe burn injury (BI) in rat liver through the histopathological and inflammatory markers analysis.METHODS: Forty-two male Wistar rats were distributed into two groups, control (C) and subjected to scald BI (SBI). The animals were euthanized one, four and 14 d post sham or 45% of the total body surface BI. Liver fragments were submitted to histopathological, morphoquantitative (hepatocyte area and cell density), ciclooxigenase-2 (COX-2) immunoexpression, and gene expression [real-time polymerase chain reaction for tumor necrosis factor (TNF)-?, inducible nitric oxide synthase (iNOS) and caspase-3] methods.RESULTS: Histopathological findings showed inflammatory process in all periods investigated and hepatocyte degeneration added to increased amount of connective tissue 14 d post injury. Hepatocyte area, the density of binucleated hepatocytes and density of sinusoidal cells of SBI groups were increased when compared with control. COX-2 immunoexpression was stronger in SBI groups. No differences were found in TNF-?, iNOS and caspase-3 gene expression.CONCLUSION: BI induces histopathological changes, upregulation of COX-2 immunoexpression, and cell proliferation in liver of rats. Twit Text FOAVip Burn injury induces histopathological changes and cell proliferation in liver of rats ????World J Hepatol http://www.kidney.de/pget.php?&tw=1&pmid=26962398 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26962398 #FOAvip English Wikipedia <ref>{{Cite pmid|26962398}}</ref> Burn injury induces histopathological changes and cell proliferation in liver of rats #MMPMID26962398 Bortolin JA; Quintana HT; Tomé Tde C; Ribeiro FAP; Ribeiro DA; de Oliveira F World J Hepatol 2016[Feb]; 8 (6): 322-30 PMID26962398show ga AIM: To investigate effects of severe burn injury (BI) in rat liver through the histopathological and inflammatory markers analysis.METHODS: Forty-two male Wistar rats were distributed into two groups, control (C) and subjected to scald BI (SBI). The animals were euthanized one, four and 14 d post sham or 45% of the total body surface BI. Liver fragments were submitted to histopathological, morphoquantitative (hepatocyte area and cell density), ciclooxigenase-2 (COX-2) immunoexpression, and gene expression [real-time polymerase chain reaction for tumor necrosis factor (TNF)-?, inducible nitric oxide synthase (iNOS) and caspase-3] methods.RESULTS: Histopathological findings showed inflammatory process in all periods investigated and hepatocyte degeneration added to increased amount of connective tissue 14 d post injury. Hepatocyte area, the density of binucleated hepatocytes and density of sinusoidal cells of SBI groups were increased when compared with control. COX-2 immunoexpression was stronger in SBI groups. No differences were found in TNF-?, iNOS and caspase-3 gene expression.CONCLUSION: BI induces histopathological changes, upregulation of COX-2 immunoexpression, and cell proliferation in liver of rats. äBurn injury induces histopathological changes and cell proliferation i(epmc).pdf DeepDyve Pubget Overpricing