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10.1016/j.ymeth.2015.11.013 http://scihub22266oqcxt.onion/10.1016/j.ymeth.2015.11.013 C4766031!4766031!26608110     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26608110&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Methods 2016 ; 96 (ä): 97-102 Nephropedia Template TP {{tp|p=26608110|t=2016. High-throughput Imaging: Focusing In On Drug Discovery in 3D |pdf=|usr=}}{{26608110}} gab.com Text High-throughput Imaging: Focusing In On Drug Discovery in 3D JO: Methods http://www.kidney.de/pget.php?&tw=1&pmid=26608110 #FOAvip 3D organotypic culture models such as organoids and multicellular tumor spheroids (MCTS) are becoming more widely used for drug discovery and toxicology screening. As a result, 3D culture technologies adapted for high-throughput screening formats are prevalent. While a multitude of assays have been reported and validated for high-throughput imaging (HTI) and high-content screening (HCS) for novel drug discovery and toxicology, limited HTI/HCS with large compound libraries have been reported. Nonetheless, 3D HTI instrumentation technology is advancing and this technology is now on the verge of allowing for 3D HCS of thousands of samples. This review focuses on the state-of-the-art high-throughput imaging systems, including hardware and software, and recent literature examples of 3D organotypic culture models employing this technology for drug discovery and toxicology screening. Twit Text FOAVip High-throughput Imaging: Focusing In On Drug Discovery in 3D ????Methods http://www.kidney.de/pget.php?&tw=1&pmid=26608110 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26608110 #FOAvip English Wikipedia <ref>{{Cite pmid|26608110}}</ref> High-throughput Imaging: Focusing In On Drug Discovery in 3D #MMPMID26608110 Li L; Zhou Q; Voss TC; Quick KL; LaBarbera DV Methods 2016[Mar]; 96 (ä): 97-102 PMID26608110show ga 3D organotypic culture models such as organoids and multicellular tumor spheroids (MCTS) are becoming more widely used for drug discovery and toxicology screening. As a result, 3D culture technologies adapted for high-throughput screening formats are prevalent. While a multitude of assays have been reported and validated for high-throughput imaging (HTI) and high-content screening (HCS) for novel drug discovery and toxicology, limited HTI/HCS with large compound libraries have been reported. Nonetheless, 3D HTI instrumentation technology is advancing and this technology is now on the verge of allowing for 3D HCS of thousands of samples. This review focuses on the state-of-the-art high-throughput imaging systems, including hardware and software, and recent literature examples of 3D organotypic culture models employing this technology for drug discovery and toxicology screening. äHigh-throughput Imaging: Focusing In On Drug Discovery in 3D (epmc).pdf DeepDyve Pubget Overpricing