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10.12688/f1000research.7665.1 http://scihub22266oqcxt.onion/10.12688/f1000research.7665.1 C4765712!4765712!26962437     free     free     free       F1000Res 2016 ; 5 (ä): ä Nephropedia Template TP {{tp|p=26962437|t=2016. Current Landscape of Antiviral Drug Discovery |pdf=|usr=}}{{26962437}} gab.com Text Current Landscape of Antiviral Drug Discovery JO: F1000Res http://www.kidney.de/pget.php?&tw=1&pmid=26962437 #FOAvip Continued discovery and development of new antiviral medications are paramount for global human health, particularly as new pathogens emerge and old ones evolve to evade current therapeutic agents. Great success has been achieved in developing effective therapies to suppress human immunodeficiency virus (HIV) and hepatitis B virus (HBV); however, the therapies are not curative and therefore current efforts in HIV and HBV drug discovery are directed toward longer-acting therapies and/or developing new mechanisms of action that could potentially lead to cure, or eradication, of the virus. Recently, exciting early clinical data have been reported for novel antivirals targeting respiratory syncytial virus (RSV) and influenza (flu). Preclinical data suggest that these new approaches may be effective in treating high-risk patients afflicted with serious RSV or flu infections. In this review, we highlight new directions in antiviral approaches for HIV, HBV, and acute respiratory virus infections. Twit Text FOAVip Current Landscape of Antiviral Drug Discovery ????F1000Res http://www.kidney.de/pget.php?&tw=1&pmid=26962437 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26962437 #FOAvip English Wikipedia <ref>{{Cite pmid|26962437}}</ref> Current Landscape of Antiviral Drug Discovery #MMPMID26962437 Blair W; Cox C F1000Res 2016[]; 5 (ä): ä PMID26962437show ga Continued discovery and development of new antiviral medications are paramount for global human health, particularly as new pathogens emerge and old ones evolve to evade current therapeutic agents. Great success has been achieved in developing effective therapies to suppress human immunodeficiency virus (HIV) and hepatitis B virus (HBV); however, the therapies are not curative and therefore current efforts in HIV and HBV drug discovery are directed toward longer-acting therapies and/or developing new mechanisms of action that could potentially lead to cure, or eradication, of the virus. Recently, exciting early clinical data have been reported for novel antivirals targeting respiratory syncytial virus (RSV) and influenza (flu). Preclinical data suggest that these new approaches may be effective in treating high-risk patients afflicted with serious RSV or flu infections. In this review, we highlight new directions in antiviral approaches for HIV, HBV, and acute respiratory virus infections. äCurrent Landscape of Antiviral Drug Discovery (epmc).pdf DeepDyve Pubget Overpricing