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10.4314/ahs.v15i3.21

http://scihub22266oqcxt.onion/10.4314/ahs.v15i3.21
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suck abstract from ncbi


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pmid26957975      Afr+Health+Sci 2015 ; 15 (3): 861-7
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  • Inducible clindamycin resistance and nasal carriage rates of Staphylococcus aureus among healthcare workers and community members #MMPMID26957975
  • Mahmoud AM; Albadawy HS; Bolis SM; Bilal NE; Ahmed AO; Ibrahim ME
  • Afr Health Sci 2015[Sep]; 15 (3): 861-7 PMID26957975show ga
  • Background: Nasal carriage of Staphylococcus aureus is becoming an increasing problem among healthcare workers and community individuals Objectives: To determine the prevalence of methicillin-resistant S. aureus (MRSA) nasal colonization and inducible clindamycin resistance (ICR) of S. aureus among healthcare workers at Soba University Hospital and community members in Khartoum State, Sudan. Methods: Five hundred nasal swabs samples were collected during March 2009 to April 2010. Isolates were identified using conventional laboratory assays and MRSA determined by the disk diffusion method. The D-test was performed for detection of ICR isolates with Clinical Laboratory Standard Institute guidelines. Results: Of the 114 S. aureus isolated, 20.2% represented MRSA. The occurrence of MRSA was significantly higher among healthcare worker than community individuals [32.7% (18/55) vs. 6.9% (5/59)] (p=0.001). Overall the 114 S. aureus isolates tested for ICR by D-test, 29 (25.4%) yielded inducible resistance. Significantly higher (p=0.026) ICR was detected among MRSA (43.5%) than methicillin-susceptible S. aureus (MSSA) (20.9%). Conclusion: MRSA nasal carriage among healthcare workers needs infection control practice in hospitals to prevent transmission of MRSA. The occurrence of ICR in S. aureus is of a great concern, D- test should be carried out routinely in our hospitals to avoid therapeutic failure.
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