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10.1155/2016/7601393 http://scihub22266oqcxt.onion/10.1155/2016/7601393 C4764747!4764747!26977316     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Pulm+Med 2016 ; 2016 (ä): ä Nephropedia Template TP {{tp|p=26977316|t=2016. The Protective Effect of Naringin against Bleomycin-Induced Pulmonary Fibrosis in Wistar Rats |pdf=|usr=}}{{26977316}} gab.com Text The Protective Effect of Naringin against Bleomycin-Induced Pulmonary Fibrosis in Wistar Rats JO: Pulm Med http://www.kidney.de/pget.php?&tw=1&pmid=26977316 #FOAvip The aim of the current study was to investigate the protective effect of naringin on bleomycin-induced pulmonary fibrosis in rats. Twenty-four Wistar rats randomly divided into four groups (control, bleomycin alone, bleomycin + naringin 40, and bleomycin + naringin 80) were used. Rats were administered a single dose of bleomycin (5?mg/kg; via the tracheal cannula) alone or followed by either naringin 40?mg/kg (orally) or naringin 80?mg/kg (orally) or water (1?mL, orally) for 14 days. Rats and lung tissue were weighed to determine the lung index. TNF-? and IL-1? levels, hydroxyproline content, and malondialdehyde (MDA) levels were assayed. Glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) activities were determined. Tissue sections were stained with hematoxylin-eosin, Masson's trichrome, and 0.1% toluidine blue. TNF-?, IL-1?, and MDA levels and hydroxyproline content significantly increased (p < 0.01) and GPx and SOD activities significantly decreased in bleomycin group (p < 0.01). Naringin at a dose of 80?mg/kg body weight significantly decreased TNF-? and IL-1? activity, hydroxyproline content, and MDA level (p < 0.01) and increased GPx and SOD activities (p < 0.05). Histological evidence supported the results. These results show that naringin has the potential of reducing the toxic effects of bleomycin and may provide supportive therapy for conventional treatment methods for idiopathic pulmonary fibrosis. Twit Text FOAVip The Protective Effect of Naringin against Bleomycin-Induced Pulmonary Fibrosis in Wistar Rats ????Pulm Med http://www.kidney.de/pget.php?&tw=1&pmid=26977316 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26977316 #FOAvip English Wikipedia <ref>{{Cite pmid|26977316}}</ref> The Protective Effect of Naringin against Bleomycin-Induced Pulmonary Fibrosis in Wistar Rats #MMPMID26977316 Turgut NH; Kara H; Elagoz S; Deveci K; Gungor H; Arslanbas E Pulm Med 2016[]; 2016 (ä): ä PMID26977316show ga The aim of the current study was to investigate the protective effect of naringin on bleomycin-induced pulmonary fibrosis in rats. Twenty-four Wistar rats randomly divided into four groups (control, bleomycin alone, bleomycin + naringin 40, and bleomycin + naringin 80) were used. Rats were administered a single dose of bleomycin (5?mg/kg; via the tracheal cannula) alone or followed by either naringin 40?mg/kg (orally) or naringin 80?mg/kg (orally) or water (1?mL, orally) for 14 days. Rats and lung tissue were weighed to determine the lung index. TNF-? and IL-1? levels, hydroxyproline content, and malondialdehyde (MDA) levels were assayed. Glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) activities were determined. Tissue sections were stained with hematoxylin-eosin, Masson's trichrome, and 0.1% toluidine blue. TNF-?, IL-1?, and MDA levels and hydroxyproline content significantly increased (p < 0.01) and GPx and SOD activities significantly decreased in bleomycin group (p < 0.01). Naringin at a dose of 80?mg/kg body weight significantly decreased TNF-? and IL-1? activity, hydroxyproline content, and MDA level (p < 0.01) and increased GPx and SOD activities (p < 0.05). Histological evidence supported the results. These results show that naringin has the potential of reducing the toxic effects of bleomycin and may provide supportive therapy for conventional treatment methods for idiopathic pulmonary fibrosis. äThe Protective Effect of Naringin against Bleomycin-Induced Pulmonary (epmc).pdf DeepDyve Pubget Overpricing