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2016 ; 4
(ä): 18
Nephropedia Template TP
gab.com Text
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English Wikipedia
Caries Experience among Adults Exposed to Low to Moderate Doses of Ionizing
Radiation in Childhood - The Tinea Capitis Cohort
#MMPMID26942172
Vered Y
; Chetrit A
; Sgan-Cohen HD
; Amitai T
; Mann J
; Even-Nir H
; Sadetzki S
Front Public Health
2016[]; 4
(ä): 18
PMID26942172
show ga
While the impact of therapeutic levels of ionizing radiation during childhood on
dental defects has been documented, the possible effect of low doses on dental
health is unknown. The study aim was to assess the association between childhood
exposure to low-moderate doses of therapeutic radiation and caries experience
among a cohort of adults 50?years following the exposure. The analysis was based
on a sample of 253 irradiated (in the treatment of tinea capitis) and 162
non-irradiated subjects. The decayed, missing, and filled teeth (DMFT) index was
assessed during a clinical dental examination and questions regarding dental care
services utilization, oral hygiene behavior, current self-perceived mouth
dryness, socio-demographic parameters, and health behavior variables were
obtained through a face-to-face interview. An ordered multivariate logistic
regression model was used to assess the association of the main independent
variable (irradiation status) and other relevant independent variables on the
increase in DMFT. Mean caries experience levels (DMFT) were 18.6?±?7.5 for
irradiated subjects compared to 16.4?±?7.2 for the non-irradiated (p?=?0.002).
Controlling for gender, age, education, income, smoking, dental visit in the last
year, and brushing teeth behavior, irradiation was associated with a 72%
increased risk for higher DMFT level (95% CI: 1.19-2.50). A quantification of the
risk by dose absorbed in the salivary gland and in the thyroid gland showed
adjusted ORs of 2.21 per 1?Gy (95% CI: 1.40-3.50) and 1.05 per 1?cGy (95% CI:
1.01-1.09), respectively. Childhood exposure to ionizing radiation (0.2-0.4?Gy)
might be associated with late outcomes of dental health. In line with the
guidelines of the American Dental Association, these results call for caution
when using dental radiographs.