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10.3389/fimmu.2016.00063 http://scihub22266oqcxt.onion/10.3389/fimmu.2016.00063 C4763042!4763042!26941742     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Immunol 2016 ; 7 (ä): ä Nephropedia Template TP {{tp|p=26941742|t=2016. Antibody Targeting of ?Steady-State? Dendritic Cells Induces Tolerance Mediated by Regulatory T Cells |pdf=|usr=}}{{26941742}} gab.com Text Antibody Targeting of Steady-State Dendritic Cells Induces Tolerance Mediated by Regulatory T Cells JO: Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=26941742 #FOAvip Dendritic cells (DCs) are often defined as pivotal inducers of immunity, but these proinflammatory properties only develop after stimulation or ex vivo manipulation of DCs. Under non-inflammatory conditions in vivo, DCs are embedded into a tissue environment and encounter a plethora of self-antigens derived from apoptotic material. This material is transported to secondary lymphoid organs. As DCs maintain their non-activated phenotype in a sterile tissue environment, interaction with T cells will induce rather regulatory T cells than effector T cells. Thus, DCs are not only inducers of immunity but are also critical for maintenance of peripheral tolerance. Therapeutically, intervention for the induction of long-lasting tolerance in several autoimmune conditions may therefore be possible by manipulating DC activation and/or targeting of DCs in their ?natural? tissue environment. Twit Text FOAVip Antibody Targeting of Steady-State Dendritic Cells Induces Tolerance Mediated by Regulatory T Cells ????Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=26941742 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26941742 #FOAvip English Wikipedia <ref>{{Cite pmid|26941742}}</ref> Antibody Targeting of ?Steady-State? Dendritic Cells Induces Tolerance Mediated by Regulatory T Cells #MMPMID26941742 Mahnke K; Ring S; Enk AH Front Immunol 2016[]; 7 (ä): ä PMID26941742show ga Dendritic cells (DCs) are often defined as pivotal inducers of immunity, but these proinflammatory properties only develop after stimulation or ex vivo manipulation of DCs. Under non-inflammatory conditions in vivo, DCs are embedded into a tissue environment and encounter a plethora of self-antigens derived from apoptotic material. This material is transported to secondary lymphoid organs. As DCs maintain their non-activated phenotype in a sterile tissue environment, interaction with T cells will induce rather regulatory T cells than effector T cells. Thus, DCs are not only inducers of immunity but are also critical for maintenance of peripheral tolerance. Therapeutically, intervention for the induction of long-lasting tolerance in several autoimmune conditions may therefore be possible by manipulating DC activation and/or targeting of DCs in their ?natural? tissue environment. äAntibody Targeting of ?Steady-State? Dendritic Cells Induces Tolerance(epmc).pdf DeepDyve Pubget Overpricing