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10.1002/wdev.213 http://scihub22266oqcxt.onion/10.1002/wdev.213 C4761274!4761274!26488117     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Wiley+Interdiscip+Rev+Dev+Biol 2016 ; 5 (2): 136-49 Nephropedia Template TP {{tp|p=26488117|t=2016. Cellular and Chromatin Dynamics of Antibody-Secreting Plasma Cells |pdf=|usr=}}{{26488117}} gab.com Text Cellular and Chromatin Dynamics of Antibody-Secreting Plasma Cells JO: Wiley Interdiscip Rev Dev Biol http://www.kidney.de/pget.php?&tw=1&pmid=26488117 #FOAvip Plasma cells are terminally differentiated B cells responsible for maintaining protective serum antibody titers. Despite their clinical importance, our understanding of the linear genomic features and chromatin structure of plasma cells is incomplete. The plasma cell differentiation program can be triggered by different signals and in multiple, diverse peripheral B cell subsets. This heterogeneity raises questions about the gene regulatory circuits required for plasma cell specification. Recently, new regulators of plasma cell differentiation have been identified and the enhancer landscapes of naïve B cells have been described. Other studies have revealed that the bone marrow niche harbors heterogeneous plasma cell subsets. Still undefined are the minimal requirements to become a plasma cell and what molecular features make peripheral B cell subsets competent to become antibody-secreting plasma cells. New technologies promise to reveal underlying chromatin configurations that promote efficient antibody secretion. Twit Text FOAVip Cellular and Chromatin Dynamics of Antibody-Secreting Plasma Cells ????Wiley Interdiscip Rev Dev Biol http://www.kidney.de/pget.php?&tw=1&pmid=26488117 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26488117 #FOAvip English Wikipedia <ref>{{Cite pmid|26488117}}</ref> Cellular and Chromatin Dynamics of Antibody-Secreting Plasma Cells #MMPMID26488117 Bortnick A; Murre C Wiley Interdiscip Rev Dev Biol 2016[Mar]; 5 (2): 136-49 PMID26488117show ga Plasma cells are terminally differentiated B cells responsible for maintaining protective serum antibody titers. Despite their clinical importance, our understanding of the linear genomic features and chromatin structure of plasma cells is incomplete. The plasma cell differentiation program can be triggered by different signals and in multiple, diverse peripheral B cell subsets. This heterogeneity raises questions about the gene regulatory circuits required for plasma cell specification. Recently, new regulators of plasma cell differentiation have been identified and the enhancer landscapes of naïve B cells have been described. Other studies have revealed that the bone marrow niche harbors heterogeneous plasma cell subsets. Still undefined are the minimal requirements to become a plasma cell and what molecular features make peripheral B cell subsets competent to become antibody-secreting plasma cells. New technologies promise to reveal underlying chromatin configurations that promote efficient antibody secretion. äCellular and Chromatin Dynamics of Antibody-Secreting Plasma Cells (epmc).pdf DeepDyve Pubget Overpricing