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10.1080/2162402X.2015.1057674

http://scihub22266oqcxt.onion/10.1080/2162402X.2015.1057674
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C4760287!4760287 !26942069
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suck abstract from ncbi

pmid26942069
      Oncoimmunology 2016 ; 5 (1 ): e1057674
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  • All that glitters is not gold: the need to consider desirable and undesirable immune aspects of oncolytic virus therapy #MMPMID26942069
  • Clements DR ; Kim Y ; Gujar SA ; Lee PW
  • Oncoimmunology 2016[]; 5 (1 ): e1057674 PMID26942069 show ga
  • Oncolytic viruses (OVs), a novel class of anticancer therapeutic agents, can overturn cancer-mediated immunosuppression and initiate antitumor immunity. Contrary to this paradigm, our recent study illustrates that oncolytic reovirus transiently augments cancer-associated immunosuppression immediately following its therapeutic administration. To achieve the optimum efficacy for OV-based anticancer therapies, the pathophysiological as well as clinical implications of this phenomenon need to be considered.
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