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Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Best+Pract+Res+Clin+Rheumatol 2015 ; 29 (2): 244-58 Nephropedia Template TP
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EVOLVING SPECTRUM OF HIV-ASSOCIATED RHEUMATIC SYNDROMES #MMPMID26362742
Fox C; Walker-Bone K
Best Pract Res Clin Rheumatol 2015[Apr]; 29 (2): 244-58 PMID26362742show ga
At the end of 2013, 35 million people worldwide were infected with HIV. The prognosis of HIV has been transformed by combination anti-retroviral therapy (cART). Providing compliance is good, use of cART has normalised the life expectancy of HIV-infected people leading to a growing population of people with chronic infection. Management of HIV patients has therefore needed to adapt in order to control viral activity but also manage long term complications of HIV and cART. Rheumatological manifestations of HIV were first described in 1989. Since, there have been case reports, case series, and epidemiological studies describing different clinical manifestations of HIV in the musculoskeletal system. This review will encompass musculoskeletal pain, fibromyalgia, systemic lupus erythematosus, and inflammatory arthritis in HIV. We will aim to report on the prevalence of these conditions and the risk factors, explore the impact of the virus on the clinical presentations and discuss implications for diagnosis and management.