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10.1177/0271678X15606723 http://scihub22266oqcxt.onion/10.1177/0271678X15606723 C4759673!4759673!26661176     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26661176&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Cereb+Blood+Flow+Metab 2016 ; 36 (2): 302-25 Nephropedia Template TP {{tp|p=26661176|t=2016. Cerebral small vessel disease: Capillary pathways to stroke and cognitive decline |pdf=|usr=}}{{26661176}} gab.com Text Cerebral small vessel disease: Capillary pathways to stroke and cognitive decline JO: J Cereb Blood Flow Metab http://www.kidney.de/pget.php?&tw=1&pmid=26661176 #FOAvip Cerebral small vessel disease (SVD) gives rise to one in five strokes worldwide and constitutes a major source of cognitive decline in the elderly. SVD is known to occur in relation to hypertension, diabetes, smoking, radiation therapy and in a range of inherited and genetic disorders, autoimmune disorders, connective tissue disorders, and infections. Until recently, changes in capillary patency and blood viscosity have received little attention in the aetiopathogenesis of SVD and the high risk of subsequent stroke and cognitive decline. Capillary flow patterns were, however, recently shown to limit the extraction efficacy of oxygen in tissue and capillary dysfunction therefore proposed as a source of stroke-like symptoms and neurodegeneration, even in the absence of physical flow-limiting vascular pathology. In this review, we examine whether capillary flow disturbances may be a shared feature of conditions that represent risk factors for SVD. We then discuss aspects of capillary dysfunction that could be prevented or alleviated and therefore might be of general benefit to patients at risk of SVD, stroke or cognitive decline. Twit Text FOAVip Cerebral small vessel disease: Capillary pathways to stroke and cognitive decline ????J Cereb Blood Flow Metab http://www.kidney.de/pget.php?&tw=1&pmid=26661176 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26661176 #FOAvip English Wikipedia <ref>{{Cite pmid|26661176}}</ref> Cerebral small vessel disease: Capillary pathways to stroke and cognitive decline #MMPMID26661176 Østergaard L; Engedal TS; Moreton F; Hansen MB; Wardlaw JM; Dalkara T; Markus HS; Muir KW J Cereb Blood Flow Metab 2016[Feb]; 36 (2): 302-25 PMID26661176show ga Cerebral small vessel disease (SVD) gives rise to one in five strokes worldwide and constitutes a major source of cognitive decline in the elderly. SVD is known to occur in relation to hypertension, diabetes, smoking, radiation therapy and in a range of inherited and genetic disorders, autoimmune disorders, connective tissue disorders, and infections. Until recently, changes in capillary patency and blood viscosity have received little attention in the aetiopathogenesis of SVD and the high risk of subsequent stroke and cognitive decline. Capillary flow patterns were, however, recently shown to limit the extraction efficacy of oxygen in tissue and capillary dysfunction therefore proposed as a source of stroke-like symptoms and neurodegeneration, even in the absence of physical flow-limiting vascular pathology. In this review, we examine whether capillary flow disturbances may be a shared feature of conditions that represent risk factors for SVD. We then discuss aspects of capillary dysfunction that could be prevented or alleviated and therefore might be of general benefit to patients at risk of SVD, stroke or cognitive decline. äCerebral small vessel disease: Capillary pathways to stroke and cognit(epmc).pdf DeepDyve Pubget Overpricing