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10.1016/j.bbadis.2015.10.014 http://scihub22266oqcxt.onion/10.1016/j.bbadis.2015.10.014 C4755861!4755861 !26499397     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26499397 &cmd=llinks): Failed to open stream: HTTP request failed! 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Regulation of cerebrospinal fluid (CSF) flow in neurodegenerative, neurovascular and neuroinflammatory disease |pdf=|usr=}}{{26499397 }} gab.com Text Regulation of cerebrospinal fluid (CSF) flow in neurodegenerative, neurovascular and neuroinflammatory disease JO: Biochim Biophys Acta http://www.kidney.de/pget.php?&tw=1&pmid=26499397 #FOAvip Cerebrospinal fluid (CSF) circulation and turnover provides a sink for the elimination of solutes from the brain interstitium, serving an important homeostatic role for the function of the central nervous system. Disruption of normal CSF circulation and turnover is believed to contribute to the development of many diseases, including neurodegenerative conditions such as Alzheimer's disease, ischemic and traumatic brain injury, and neuroinflammatory conditions such as multiple sclerosis. Recent insights into CSF biology suggesting that CSF and interstitial fluid exchange along a brain-wide network of perivascular spaces termed the 'glymphatic' system suggest that CSF circulation may interact intimately with glial and vascular function to regulate basic aspects of brain function. Dysfunction within this glial vascular network, which is a feature of the aging and injured brain, is a potentially critical link between brain injury, neuroinflammation and the development of chronic neurodegeneration. Ongoing research within this field may provide a powerful new framework for understanding the common links between neurodegenerative, neurovascular and neuroinflammatory disease, in addition to providing potentially novel therapeutic targets for these conditions. This article is part of a Special Issue entitled: Neuro Inflammation edited by Helga E. de Vries and Markus Schwaninger. Twit Text FOAVip Regulation of cerebrospinal fluid (CSF) flow in neurodegenerative, neurovascular and neuroinflammatory disease ????Biochim Biophys Acta http://www.kidney.de/pget.php?&tw=1&pmid=26499397 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26499397 #FOAvip English Wikipedia <ref>{{Cite pmid|26499397 }}</ref> Regulation of cerebrospinal fluid (CSF) flow in neurodegenerative, neurovascular and neuroinflammatory disease #MMPMID26499397 Simon MJ ; Iliff JJ Biochim Biophys Acta 2016[Mar]; 1862 (3 ): 442-51 PMID26499397 show ga Cerebrospinal fluid (CSF) circulation and turnover provides a sink for the elimination of solutes from the brain interstitium, serving an important homeostatic role for the function of the central nervous system. Disruption of normal CSF circulation and turnover is believed to contribute to the development of many diseases, including neurodegenerative conditions such as Alzheimer's disease, ischemic and traumatic brain injury, and neuroinflammatory conditions such as multiple sclerosis. Recent insights into CSF biology suggesting that CSF and interstitial fluid exchange along a brain-wide network of perivascular spaces termed the 'glymphatic' system suggest that CSF circulation may interact intimately with glial and vascular function to regulate basic aspects of brain function. Dysfunction within this glial vascular network, which is a feature of the aging and injured brain, is a potentially critical link between brain injury, neuroinflammation and the development of chronic neurodegeneration. Ongoing research within this field may provide a powerful new framework for understanding the common links between neurodegenerative, neurovascular and neuroinflammatory disease, in addition to providing potentially novel therapeutic targets for these conditions. This article is part of a Special Issue entitled: Neuro Inflammation edited by Helga E. de Vries and Markus Schwaninger. |Alzheimer Disease/*cerebrospinal fluid/pathology [MESH] |Animals [MESH] |Brain Ischemia/*cerebrospinal fluid/pathology [MESH] |Brain/blood supply/pathology [MESH] |Humans [MESH] |Inflammation/cerebrospinal fluid/pathology [MESH] |Lymphatic Vessels/pathology [MESH]Regulation of cerebrospinal fluid (CSF) flow in neurodegenerative, neu(epmc).pdf DeepDyve Pubget Overpricing