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10.1111/imm.12561 http://scihub22266oqcxt.onion/10.1111/imm.12561 C4754612!4754612!26643733     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Immunology 2016 ; 147 (3): 285-91 Nephropedia Template TP {{tp|p=26643733|t=2016. The emerging roles of the STING adaptor protein in immunity and diseases |pdf=|usr=}}{{26643733}} gab.com Text The emerging roles of the STING adaptor protein in immunity and diseases JO: Immunology http://www.kidney.de/pget.php?&tw=1&pmid=26643733 #FOAvip DNA that gains access to the cytoplasm generally serves as a danger signal for the hosts. An emerging paradigm for responding to cytosolic DNAs centres on the endoplasmic reticulum?resident protein stimulator of interferon genes (STING, also known as MITA, ERIS or MPYS), the hub adaptor of the recently identified DNA sensors. Dynamic regulations of STING action are critical for shaping innate immune responses against microbial infections, as well as for preventing autoimmune diseases. STING is also indispensable for the detection of immunogenic tumours. A deeper understanding of STING modulations could be instrumental for developing novel immunotherapeutic strategies against infectious, autoimmune and cancerous diseases. In this review, we summarize the latest advances on the role of STING in the DNA?triggered immune reactions, and underscore the critical issues that remain to be resolved in future studies. Twit Text FOAVip The emerging roles of the STING adaptor protein in immunity and diseases ????Immunology http://www.kidney.de/pget.php?&tw=1&pmid=26643733 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26643733 #FOAvip English Wikipedia <ref>{{Cite pmid|26643733}}</ref> The emerging roles of the STING adaptor protein in immunity and diseases #MMPMID26643733 Liu X; Wang C Immunology 2016[Mar]; 147 (3): 285-91 PMID26643733show ga DNA that gains access to the cytoplasm generally serves as a danger signal for the hosts. An emerging paradigm for responding to cytosolic DNAs centres on the endoplasmic reticulum?resident protein stimulator of interferon genes (STING, also known as MITA, ERIS or MPYS), the hub adaptor of the recently identified DNA sensors. Dynamic regulations of STING action are critical for shaping innate immune responses against microbial infections, as well as for preventing autoimmune diseases. STING is also indispensable for the detection of immunogenic tumours. A deeper understanding of STING modulations could be instrumental for developing novel immunotherapeutic strategies against infectious, autoimmune and cancerous diseases. In this review, we summarize the latest advances on the role of STING in the DNA?triggered immune reactions, and underscore the critical issues that remain to be resolved in future studies. äThe emerging roles of the STING adaptor protein in immunity and diseas(epmc).pdf DeepDyve Pubget Overpricing