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10.1093/jb/mvv081 http://scihub22266oqcxt.onion/10.1093/jb/mvv081 C4751232!4751232!26261051     free     free     free       J+Biochem 2015 ; 158 (5): 355-65 Nephropedia Template TP {{tp|p=26261051|t=2015. Non-canonical WNT signalling in the lung |pdf=|usr=}}{{26261051}} gab.com Text Non-canonical WNT signalling in the lung JO: J Biochem http://www.kidney.de/pget.php?&tw=1&pmid=26261051 #FOAvip The role of WNT signalling in metazoan organogenesis has been a topic of widespread interest. In the lung, while the role of canonical WNT signalling has been examined in some detail by multiple studies, the non-canonical WNT signalling has received limited attention. Reliable evidence shows that this important signalling mechanism constitutes a major regulatory pathway in lung development. In addition, accumulating evidence has also shown that the non-canonical WNT pathway is critical for maintaining lung homeostasis and that aberrant activation of this pathway may underlie several debilitating lung diseases. Functional analyses have further revealed that the non-canonical WNT pathway regulates multiple cellular activities in the lung that are dependent on the specific cellular context. In most cell types, non-canonical WNT signalling regulates canonical WNT activity, which is also critical for many aspects of lung biology. This review will summarize what is currently known about the role of non-canonical WNT signalling in lung development, homeostasis and pathogenesis of disease. Twit Text FOAVip Non-canonical WNT signalling in the lung ????J Biochem http://www.kidney.de/pget.php?&tw=1&pmid=26261051 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26261051 #FOAvip English Wikipedia <ref>{{Cite pmid|26261051}}</ref> Non-canonical WNT signalling in the lung #MMPMID26261051 Li C; Bellusci S; Borok Z; Minoo P J Biochem 2015[Nov]; 158 (5): 355-65 PMID26261051show ga The role of WNT signalling in metazoan organogenesis has been a topic of widespread interest. In the lung, while the role of canonical WNT signalling has been examined in some detail by multiple studies, the non-canonical WNT signalling has received limited attention. Reliable evidence shows that this important signalling mechanism constitutes a major regulatory pathway in lung development. In addition, accumulating evidence has also shown that the non-canonical WNT pathway is critical for maintaining lung homeostasis and that aberrant activation of this pathway may underlie several debilitating lung diseases. Functional analyses have further revealed that the non-canonical WNT pathway regulates multiple cellular activities in the lung that are dependent on the specific cellular context. In most cell types, non-canonical WNT signalling regulates canonical WNT activity, which is also critical for many aspects of lung biology. This review will summarize what is currently known about the role of non-canonical WNT signalling in lung development, homeostasis and pathogenesis of disease. äNon-canonical WNT signalling in the lung (epmc).pdf DeepDyve Pubget Overpricing