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10.1155/2016/2973274 http://scihub22266oqcxt.onion/10.1155/2016/2973274 C4749835!4749835!26941796     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Toxicol 2016 ; 2016 (ä): ä Nephropedia Template TP {{tp|p=26941796|t=2016. Histopathological Study of Cyclosporine Pulmonary Toxicity in Rats |pdf=|usr=}}{{26941796}} gab.com Text Histopathological Study of Cyclosporine Pulmonary Toxicity in Rats JO: J Toxicol http://www.kidney.de/pget.php?&tw=1&pmid=26941796 #FOAvip Cyclosporine is considered one of the common worldwide immunosuppressive drugs that are used for allograft rejection prevention. However, articles that address adverse effects of cyclosporine use on the vital organs such as lung are still few. This study aims to investigate pulmonary toxic effect of cyclosporine in rats by assessment of pulmonary histopathological changes using light and electron microscope examination. Sixty male adult albino rats were divided into three groups; each group consists of twenty rats. The first received physiological saline while the second and third groups received 25 and 40?mg/kg/day of cyclosporine, respectively, by gastric gavage for forty-five days. Cyclosporine reduced the lung and body weight with shrinkage or pyknotic nucleus of pneumocyte type II, degeneration of alveoli and interalveolar septum beside microvilli on the alveolar surface, emphysema, inflammatory cellular infiltration, pulmonary blood vessels congestion, and increase of fibrous tissues in the interstitial tissues and around alveoli with negative Periodic Acid-Schiff staining. Prolonged use of cyclosporine induced pulmonary ultrastructural and histopathological changes with the lung and body weight reduction depending on its dose. Twit Text FOAVip Histopathological Study of Cyclosporine Pulmonary Toxicity in Rats ????J Toxicol http://www.kidney.de/pget.php?&tw=1&pmid=26941796 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26941796 #FOAvip English Wikipedia <ref>{{Cite pmid|26941796}}</ref> Histopathological Study of Cyclosporine Pulmonary Toxicity in Rats #MMPMID26941796 Elshama SS; EL-Kenawy AEM; Osman HEH J Toxicol 2016[]; 2016 (ä): ä PMID26941796show ga Cyclosporine is considered one of the common worldwide immunosuppressive drugs that are used for allograft rejection prevention. However, articles that address adverse effects of cyclosporine use on the vital organs such as lung are still few. This study aims to investigate pulmonary toxic effect of cyclosporine in rats by assessment of pulmonary histopathological changes using light and electron microscope examination. Sixty male adult albino rats were divided into three groups; each group consists of twenty rats. The first received physiological saline while the second and third groups received 25 and 40?mg/kg/day of cyclosporine, respectively, by gastric gavage for forty-five days. Cyclosporine reduced the lung and body weight with shrinkage or pyknotic nucleus of pneumocyte type II, degeneration of alveoli and interalveolar septum beside microvilli on the alveolar surface, emphysema, inflammatory cellular infiltration, pulmonary blood vessels congestion, and increase of fibrous tissues in the interstitial tissues and around alveoli with negative Periodic Acid-Schiff staining. Prolonged use of cyclosporine induced pulmonary ultrastructural and histopathological changes with the lung and body weight reduction depending on its dose. äHistopathological Study of Cyclosporine Pulmonary Toxicity in Rats (epmc).pdf DeepDyve Pubget Overpricing