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10.1016/j.celrep.2016.01.006 http://scihub22266oqcxt.onion/10.1016/j.celrep.2016.01.006 C4749453!4749453!26832414     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell+Rep 2016 ; 14 (5): 1018-24 Nephropedia Template TP {{tp|p=26832414|t=2016. Condensin Promotes Position Effects within Tandem DNA Repeats via the RITS complex |pdf=|usr=}}{{26832414}} gab.com Text Condensin Promotes Position Effects within Tandem DNA Repeats via the RITS complex JO: Cell Rep http://www.kidney.de/pget.php?&tw=1&pmid=26832414 #FOAvip Tandem repetitive DNA is highly abundant in eukaryotic genomes, and contributes to transcription control and genome stability. However, how the individual sequences within tandem repeats behave remains largely unknown. Here we develop a collection of fission yeast strains with a reporter gene inserted at different units in a tandem repeat array. We show that, contrary to what is usually assumed, transcriptional silencing and replication timing among the individual repeats differ significantly. RNAi-mediated H3K9 methylation is essential for the silencing position effect. A short hairpin RNA of ura4+ induces silencing in trans within the tandem array in a position-dependent manner. Importantly, the position effect depends on the condensin subunit, cut3+. Cut3 promotes the position effect via interaction with the RNA-induced transcriptional silencing (RITS) complex. This study reveals variations in silencing within tandem DNA repeats and provides mechanistic insights into how DNA repeats at the individual level are regulated. Twit Text FOAVip Condensin Promotes Position Effects within Tandem DNA Repeats via the RITS complex ????Cell Rep http://www.kidney.de/pget.php?&tw=1&pmid=26832414 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26832414 #FOAvip English Wikipedia <ref>{{Cite pmid|26832414}}</ref> Condensin Promotes Position Effects within Tandem DNA Repeats via the RITS complex #MMPMID26832414 He H; Zhang S; Wang D; Hochwagen A; Li F Cell Rep 2016[Feb]; 14 (5): 1018-24 PMID26832414show ga Tandem repetitive DNA is highly abundant in eukaryotic genomes, and contributes to transcription control and genome stability. However, how the individual sequences within tandem repeats behave remains largely unknown. Here we develop a collection of fission yeast strains with a reporter gene inserted at different units in a tandem repeat array. We show that, contrary to what is usually assumed, transcriptional silencing and replication timing among the individual repeats differ significantly. RNAi-mediated H3K9 methylation is essential for the silencing position effect. A short hairpin RNA of ura4+ induces silencing in trans within the tandem array in a position-dependent manner. Importantly, the position effect depends on the condensin subunit, cut3+. Cut3 promotes the position effect via interaction with the RNA-induced transcriptional silencing (RITS) complex. This study reveals variations in silencing within tandem DNA repeats and provides mechanistic insights into how DNA repeats at the individual level are regulated. äCondensin Promotes Position Effects within Tandem DNA Repeats via the (epmc).pdf DeepDyve Pubget Overpricing