Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26844475
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26844475
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Medicine+(Baltimore)
2016 ; 95
(5
): e2627
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Distribution of Fatal Vibrio Vulnificus Necrotizing Skin and Soft-Tissue
Infections: A Systematic Review and Meta-Analysis
#MMPMID26844475
Huang KC
; Weng HH
; Yang TY
; Chang TS
; Huang TW
; Lee MS
Medicine (Baltimore)
2016[Feb]; 95
(5
): e2627
PMID26844475
show ga
Vibrio vulnificus necrotizing skin and soft tissue infections (VNSSTIs), which
have increased significantly over the past few decades, are still highly lethal
and disabling diseases despite advancing antibiotic and infection control
practices. We, therefore, examined the spatiotemporal distribution of worldwide
reported episodes and associated mortality rates of VNSSTIs between 1966 and
2014. The PubMed and Cochrane Library databases were systematically searched for
observational studies on patients with VNSSTIs. The primary outcome was all-cause
mortality. We did random-effects meta-analysis to obtain estimates for primary
outcomes; the estimates are presented as means plus a 95% confidence interval
(CI). Data from the selected studies were also extracted and pooled for
correlation analyses.Nineteen studies of 2227 total patients with VNSSTIs were
analyzed. More than 95% of the episodes occurred in the subtropical western
Pacific and Atlantic coastal regions of the northern hemisphere. While the number
of cases and the number of deaths were not correlated with the study period
(rs?=?0.476 and 0.310, P?=?0.233 and 0.456, respectively), the 5-year mortality
rate was significantly negatively correlated with them (rs?=?-0.905, P?=?0.002).
Even so, the pooled estimate of total mortality rates from the random-effects
meta-analysis was as high as 37.2% (95% CI: 0.265-0.479).These data suggest that
VNSSTIs are always an important public health problem and will become more
critical and urgent because of global warming. Knowing the current distribution
of VNSSTIs will help focus education, policy measures, early clinical diagnosis,
and appropriate medical and surgical treatment for them.