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10.1016/j.gpb.2015.08.005

http://scihub22266oqcxt.onion/10.1016/j.gpb.2015.08.005
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C4747650!4747650!26751805
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suck abstract from ncbi

pmid26751805      Genomics+Proteomics+Bioinformatics 2015 ; 13 (6): 345-54
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  • Urinary Biomarkers of Brain Diseases #MMPMID26751805
  • An M; Gao Y
  • Genomics Proteomics Bioinformatics 2015[Dec]; 13 (6): 345-54 PMID26751805show ga
  • Biomarkers are the measurable changes associated with a physiological or pathophysiological process. Unlike blood, urine is not subject to homeostatic mechanisms. Therefore, greater fluctuations could occur in urine than in blood, better reflecting the changes in human body. The roadmap of urine biomarker era was proposed. Although urine analysis has been attempted for clinical diagnosis, and urine has been monitored during the progression of many diseases, particularly urinary system diseases, whether urine can reflect brain disease status remains uncertain. As some biomarkers of brain diseases can be detected in the body fluids such as cerebrospinal fluid and blood, there is a possibility that urine also contain biomarkers of brain diseases. This review summarizes the clues of brain diseases reflected in the urine proteome and metabolome.
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