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10.1016/j.gpb.2015.12.001 http://scihub22266oqcxt.onion/10.1016/j.gpb.2015.12.001 C4747648!4747648!26762955     free     free     free Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Genomics+Proteomics+Bioinformatics 2015 ; 13 (6): 336-44 Nephropedia Template TP {{tp|p=26762955|t=2015. Genome Editing and Its Applications in Model Organisms |pdf=|usr=}}{{26762955}} gab.com Text Genome Editing and Its Applications in Model Organisms JO: Genomics Proteomics Bioinformatics http://www.kidney.de/pget.php?&tw=1&pmid=26762955 #FOAvip Technological advances are important for innovative biological research. Development of molecular tools for DNA manipulation, such as zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and the clustered regularly-interspaced short palindromic repeat (CRISPR)/CRISPR-associated (Cas), has revolutionized genome editing. These approaches can be used to develop potential therapeutic strategies to effectively treat heritable diseases. In the last few years, substantial progress has been made in CRISPR/Cas technology, including technical improvements and wide application in many model systems. This review describes recent advancements in genome editing with a particular focus on CRISPR/Cas, covering the underlying principles, technological optimization, and its application in zebrafish and other model organisms, disease modeling, and gene therapy used for personalized medicine. Twit Text FOAVip Genome Editing and Its Applications in Model Organisms ????Genomics Proteomics Bioinformatics http://www.kidney.de/pget.php?&tw=1&pmid=26762955 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26762955 #FOAvip English Wikipedia <ref>{{Cite pmid|26762955}}</ref> Genome Editing and Its Applications in Model Organisms #MMPMID26762955 Ma D; Liu F Genomics Proteomics Bioinformatics 2015[Dec]; 13 (6): 336-44 PMID26762955show ga Technological advances are important for innovative biological research. Development of molecular tools for DNA manipulation, such as zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and the clustered regularly-interspaced short palindromic repeat (CRISPR)/CRISPR-associated (Cas), has revolutionized genome editing. These approaches can be used to develop potential therapeutic strategies to effectively treat heritable diseases. In the last few years, substantial progress has been made in CRISPR/Cas technology, including technical improvements and wide application in many model systems. This review describes recent advancements in genome editing with a particular focus on CRISPR/Cas, covering the underlying principles, technological optimization, and its application in zebrafish and other model organisms, disease modeling, and gene therapy used for personalized medicine. äGenome Editing and Its Applications in Model Organisms (epmc).pdf DeepDyve Pubget Overpricing