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http://scihub22266oqcxt.onion/ C4741921!4741921!26452221     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Oncotarget 2015 ; 6 (35): 37151-68 Nephropedia Template TP {{tp|p=26452221|t=2015. Tumor-derived exosomes in cancer progression and treatment failure |pdf=|usr=}}{{26452221}} gab.com Text Tumor-derived exosomes in cancer progression and treatment failure JO: Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=26452221 #FOAvip Exosomes have diameter within the range of 30-100nm and spherical to cup-shaped nanoparticles with specific surface molecular characteristics, such as CD9 and CD63. These vesicles are present in nearly all human body fluids, including blood plasma/serum, saliva, breast milk, cerebrospinal fluid, urine, semen, and particularly enriched in tumor microenvironment. Exosomes contain multiple proteins, DNA, mRNA, miRNA, long non-coding RNA, and even genetic materials of viruses/prions. These materials are biochemically and functionally distinct and can be transferred to a recipient cell where they regulate protein expression and signaling pathways. Recently, exosomes are demonstrated to have a close relationship with tumor development and metastasis. Exosomes influence therapeutic effect in cancer patients. In this review, we describe the biogenesis, composition, and function of exosomes. The mechanism on how tumor-derived exosomes contribute to cancer progression and clinical treatment failure is also described, with special focus on their potential applications in cancer therapy. Twit Text FOAVip Tumor-derived exosomes in cancer progression and treatment failure ????Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=26452221 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26452221 #FOAvip English Wikipedia <ref>{{Cite pmid|26452221}}</ref> Tumor-derived exosomes in cancer progression and treatment failure #MMPMID26452221 Yu S; Cao H; Shen B; Feng J Oncotarget 2015[Nov]; 6 (35): 37151-68 PMID26452221show ga Exosomes have diameter within the range of 30-100nm and spherical to cup-shaped nanoparticles with specific surface molecular characteristics, such as CD9 and CD63. These vesicles are present in nearly all human body fluids, including blood plasma/serum, saliva, breast milk, cerebrospinal fluid, urine, semen, and particularly enriched in tumor microenvironment. Exosomes contain multiple proteins, DNA, mRNA, miRNA, long non-coding RNA, and even genetic materials of viruses/prions. These materials are biochemically and functionally distinct and can be transferred to a recipient cell where they regulate protein expression and signaling pathways. Recently, exosomes are demonstrated to have a close relationship with tumor development and metastasis. Exosomes influence therapeutic effect in cancer patients. In this review, we describe the biogenesis, composition, and function of exosomes. The mechanism on how tumor-derived exosomes contribute to cancer progression and clinical treatment failure is also described, with special focus on their potential applications in cancer therapy. äTumor-derived exosomes in cancer progression and treatment failure (epmc).pdf DeepDyve Pubget Overpricing