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http://scihub22266oqcxt.onion/ C4741561!4741561!26362400     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26362400&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Oncotarget 2015 ; 6 (31): 30675-703 Nephropedia Template TP {{tp|p=26362400|t=2015. Progresses towards safe and efficient gene therapy vectors |pdf=|usr=}}{{26362400}} gab.com Text Progresses towards safe and efficient gene therapy vectors JO: Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=26362400 #FOAvip The emergence of genetic engineering at the beginning of the 1970?s opened the era of biomedical technologies, which aims to improve human health using genetic manipulation techniques in a clinical context. Gene therapy represents an innovating and appealing strategy for treatment of human diseases, which utilizes vehicles or vectors for delivering therapeutic genes into the patients' body. However, a few past unsuccessful events that negatively marked the beginning of gene therapy resulted in the need for further studies regarding the design and biology of gene therapy vectors, so that this innovating treatment approach can successfully move from bench to bedside. In this paper, we review the major gene delivery vectors and recent improvements made in their design meant to overcome the issues that commonly arise with the use of gene therapy vectors. At the end of the manuscript, we summarized the main advantages and disadvantages of common gene therapy vectors and we discuss possible future directions for potential therapeutic vectors. Twit Text FOAVip Progresses towards safe and efficient gene therapy vectors ????Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=26362400 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26362400 #FOAvip English Wikipedia <ref>{{Cite pmid|26362400}}</ref> Progresses towards safe and efficient gene therapy vectors #MMPMID26362400 Chira S; Jackson CS; Oprea I; Ozturk F; Pepper MS; Diaconu I; Braicu C; Raduly LZ; Calin GA; Berindan-Neagoe I Oncotarget 2015[Oct]; 6 (31): 30675-703 PMID26362400show ga The emergence of genetic engineering at the beginning of the 1970?s opened the era of biomedical technologies, which aims to improve human health using genetic manipulation techniques in a clinical context. Gene therapy represents an innovating and appealing strategy for treatment of human diseases, which utilizes vehicles or vectors for delivering therapeutic genes into the patients' body. However, a few past unsuccessful events that negatively marked the beginning of gene therapy resulted in the need for further studies regarding the design and biology of gene therapy vectors, so that this innovating treatment approach can successfully move from bench to bedside. In this paper, we review the major gene delivery vectors and recent improvements made in their design meant to overcome the issues that commonly arise with the use of gene therapy vectors. At the end of the manuscript, we summarized the main advantages and disadvantages of common gene therapy vectors and we discuss possible future directions for potential therapeutic vectors. äProgresses towards safe and efficient gene therapy vectors (epmc).pdf DeepDyve Pubget Overpricing