Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1038/ncomms10217 http://scihub22266oqcxt.onion/10.1038/ncomms10217 C4729827!4729827!26732171     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26732171&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nat+Commun 2016 ; 7 (ä): ä Nephropedia Template TP {{tp|p=26732171|t=2016. Nanopore sensing at ultra-low concentrations using single-molecule dielectrophoretic trapping |pdf=|usr=}}{{26732171}} gab.com Text Nanopore sensing at ultra-low concentrations using single-molecule dielectrophoretic trapping JO: Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=26732171 #FOAvip Single-molecule techniques are being developed with the exciting prospect of revolutionizing the healthcare industry by generating vast amounts of genetic and proteomic data. One exceptionally promising route is in the use of nanopore sensors. However, a well-known complexity is that detection and capture is predominantly diffusion limited. This problem is compounded when taking into account the capture volume of a nanopore, typically 108?1010 times smaller than the sample volume. To rectify this disproportionate ratio, we demonstrate a simple, yet powerful, method based on coupling single-molecule dielectrophoretic trapping to nanopore sensing. We show that DNA can be captured from a controllable, but typically much larger, volume and concentrated at the tip of a metallic nanopore. This enables the detection of single molecules at concentrations as low as 5?fM, which is approximately a 103 reduction in the limit of detection compared with existing methods, while still maintaining efficient throughput. Twit Text FOAVip Nanopore sensing at ultra-low concentrations using single-molecule dielectrophoretic trapping ????Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=26732171 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26732171 #FOAvip English Wikipedia <ref>{{Cite pmid|26732171}}</ref> Nanopore sensing at ultra-low concentrations using single-molecule dielectrophoretic trapping #MMPMID26732171 Freedman KJ; Otto LM; Ivanov AP; Barik A; Oh SH; Edel JB Nat Commun 2016[]; 7 (ä): ä PMID26732171show ga Single-molecule techniques are being developed with the exciting prospect of revolutionizing the healthcare industry by generating vast amounts of genetic and proteomic data. One exceptionally promising route is in the use of nanopore sensors. However, a well-known complexity is that detection and capture is predominantly diffusion limited. This problem is compounded when taking into account the capture volume of a nanopore, typically 108?1010 times smaller than the sample volume. To rectify this disproportionate ratio, we demonstrate a simple, yet powerful, method based on coupling single-molecule dielectrophoretic trapping to nanopore sensing. We show that DNA can be captured from a controllable, but typically much larger, volume and concentrated at the tip of a metallic nanopore. This enables the detection of single molecules at concentrations as low as 5?fM, which is approximately a 103 reduction in the limit of detection compared with existing methods, while still maintaining efficient throughput. äNanopore sensing at ultra-low concentrations using single-molecule die(epmc).pdf DeepDyve Pubget Overpricing