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10.1126/science.aac9593 http://scihub22266oqcxt.onion/10.1126/science.aac9593 C4720139!4720139!26472762     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Science 2015 ; 350 (6263): 981-5 Nephropedia Template TP {{tp|p=26472762|t=2015. Tissue residency of innate lymphoid cells in lymphoid and non-lymphoid organs |pdf=|usr=}}{{26472762}} gab.com Text Tissue residency of innate lymphoid cells in lymphoid and non-lymphoid organs JO: Science http://www.kidney.de/pget.php?&tw=1&pmid=26472762 #FOAvip Innate lymphoid cells (ILC) contribute to barrier immunity, tissue homeostasis, and immune regulation at various anatomical sites throughout the body. How ILCs maintain their presence in lymphoid and peripheral tissues is currently unknown. We found that in the lymphoid and non-lymphoid organs of adult mice, ILC are tissue-resident cells that were maintained and expanded locally under physiologic conditions, upon systemic perturbation of immune homeostasis, and during acute helminth infection. However, at later time points post-infection, cells from hematogenous sources helped to partially replenish the pool of resident ILCs. Thus, ILC are maintained by self-renewal in broadly different microenvironments and physiological settings. Such an extreme ?sedentary? lifestyle is consistent with the proposed roles of ILCs as sentinels and local keepers of tissue function. Twit Text FOAVip Tissue residency of innate lymphoid cells in lymphoid and non-lymphoid organs ????Science http://www.kidney.de/pget.php?&tw=1&pmid=26472762 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26472762 #FOAvip English Wikipedia <ref>{{Cite pmid|26472762}}</ref> Tissue residency of innate lymphoid cells in lymphoid and non-lymphoid organs #MMPMID26472762 Gasteiger G; Fan X; Dikiy S; Lee SY; Rudensky AY Science 2015[Nov]; 350 (6263): 981-5 PMID26472762show ga Innate lymphoid cells (ILC) contribute to barrier immunity, tissue homeostasis, and immune regulation at various anatomical sites throughout the body. How ILCs maintain their presence in lymphoid and peripheral tissues is currently unknown. We found that in the lymphoid and non-lymphoid organs of adult mice, ILC are tissue-resident cells that were maintained and expanded locally under physiologic conditions, upon systemic perturbation of immune homeostasis, and during acute helminth infection. However, at later time points post-infection, cells from hematogenous sources helped to partially replenish the pool of resident ILCs. Thus, ILC are maintained by self-renewal in broadly different microenvironments and physiological settings. Such an extreme ?sedentary? lifestyle is consistent with the proposed roles of ILCs as sentinels and local keepers of tissue function. äTissue residency of innate lymphoid cells in lymphoid and non-lymphoid(epmc).pdf DeepDyve Pubget Overpricing