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10.1091/mbc.E15-05-0272

http://scihub22266oqcxt.onion/10.1091/mbc.E15-05-0272
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C4713134!4713134!26582390
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suck abstract from ncbi


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pmid26582390      Mol+Biol+Cell 2016 ; 27 (2): 321-33
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  • mTOR controls lysosome tubulation and antigen presentation in macrophages and dendritic cells #MMPMID26582390
  • Saric A; Hipolito VEB; Kay JG; Canton J; Antonescu CN; Botelho RJ
  • Mol Biol Cell 2016[Jan]; 27 (2): 321-33 PMID26582390show ga
  • LPS causes lysosome tubulation in macrophages and dendritic cells. The PI3K-Akt-mTOR pathway is necessary for LPS-induced lysosome tubulation, and mTOR is required for MHC-II presentation in dendritic cells. Evidence shows that mTOR may control lysosome tubulation by modulating microtubule motor activity through Arl8b.
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