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10.1074/jbc.M115.667899

http://scihub22266oqcxt.onion/10.1074/jbc.M115.667899
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C4705988!4705988!26504086
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suck abstract from ncbi


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pmid26504086      J+Biol+Chem 2015 ; 290 (50): 29882-92
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  • Trpm7 Protein Contributes to Intercellular Junction Formation in Mouse Urothelium* #MMPMID26504086
  • Watanabe M; Suzuki Y; Uchida K; Miyazaki N; Murata K; Matsumoto S; Kakizaki H; Tominaga M
  • J Biol Chem 2015[Dec]; 290 (50): 29882-92 PMID26504086show ga
  • Background: Transient receptor potential melastatin 7 (Trpm7) is a Ca2+-permeable channel with a kinase domain that is implicated in cell migration and adhesion.Results: Urothelium-specific Trpm7 knock-out caused immature intercellular junctions, inflammation, and smaller voided volume.Conclusion: Trpm7 contributes to the intercellular junction formation in the urothelium.Significance: These findings might provide the first evidence for the significance of Trpm7 in bladder function in vivo.
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