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10.1146/annurev-biochem-052610-094414 http://scihub22266oqcxt.onion/10.1146/annurev-biochem-052610-094414 C4696014!4696014!23746253     free     free     free       Annu+Rev+Biochem 2013 ; 82 (ä): 25-54 Nephropedia Template TP {{tp|p=23746253|t=2013. Mechanisms for Initiating Cellular DNA Replication |pdf=|usr=}}{{23746253}} gab.com Text Mechanisms for Initiating Cellular DNA Replication JO: Annu Rev Biochem http://www.kidney.de/pget.php?&tw=1&pmid=23746253 #FOAvip The initiation of DNA replication represents a committing step to cell proliferation. Appropriate replication onset depends on multiprotein complexes that help properly distinguish origin regions, generate nascent replication bubbles, and promote replisome formation. This review describes initiation systems employed by bacteria, archaea, and eukaryotes, with a focus on comparing and contrasting molecular mechanisms among organisms. Although commonalities can be found in the functional domains and strategies used to carry out and regulate initiation, many key participants have markedly different activities and appear to have evolved convergently. Despite significant advances in the field, major questions still persist in understanding how initiation programs are executed at the molecular level. Twit Text FOAVip Mechanisms for Initiating Cellular DNA Replication ????Annu Rev Biochem http://www.kidney.de/pget.php?&tw=1&pmid=23746253 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=23746253 #FOAvip English Wikipedia <ref>{{Cite pmid|23746253}}</ref> Mechanisms for Initiating Cellular DNA Replication #MMPMID23746253 Costa A; Hood IV; Berger JM Annu Rev Biochem 2013[]; 82 (ä): 25-54 PMID23746253show ga The initiation of DNA replication represents a committing step to cell proliferation. Appropriate replication onset depends on multiprotein complexes that help properly distinguish origin regions, generate nascent replication bubbles, and promote replisome formation. This review describes initiation systems employed by bacteria, archaea, and eukaryotes, with a focus on comparing and contrasting molecular mechanisms among organisms. Although commonalities can be found in the functional domains and strategies used to carry out and regulate initiation, many key participants have markedly different activities and appear to have evolved convergently. Despite significant advances in the field, major questions still persist in understanding how initiation programs are executed at the molecular level. äMechanisms for Initiating Cellular DNA Replication (epmc).pdf DeepDyve Pubget Overpricing