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10.1158/2326-6066.CIR-14-0161

http://scihub22266oqcxt.onion/10.1158/2326-6066.CIR-14-0161
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C4692051!4692051!25367977
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suck abstract from ncbi

pmid25367977      Cancer+Immunol+Res 2014 ; 2 (11): 1023-33
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  • The immunological synapse #MMPMID25367977
  • Dustin ML
  • Cancer Immunol Res 2014[Nov]; 2 (11): 1023-33 PMID25367977show ga
  • The molecular interactions underlying regulation of the immune response take place in a nano-scale gap between T cells and antigen presenting cells, termed the immunological synapse. If these interactions are regulated appropriately, the host is defended against a wide range of pathogens and deranged host cells. If these interactions are dis-regulated, the host is susceptible to pathogens or tumor escape at one extreme and autoimmunity at the other. Treatments targeting the synapse have helped to establish immunotherapy as a mainstream element in cancer treatment. This Masters primer will cover the basics of the immunological synapse and some of the applications to tumor immunology.
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