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10.1007/s00467-015-3065-y http://scihub22266oqcxt.onion/10.1007/s00467-015-3065-y C4689752!4689752 !25724169     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25724169 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Pediatr+Nephrol 2016 ; 31 (2 ): 185-94 Nephropedia Template TP {{tp|p=25724169 |t=2016. Primary hypertension is a disease of premature vascular aging associated with neuro-immuno-metabolic abnormalities |pdf=|usr=}}{{25724169 }} gab.com Text Primary hypertension is a disease of premature vascular aging associated with neuro-immuno-metabolic abnormalities JO: Pediatr Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=25724169 #FOAvip There is an increasing amount of data indicating that primary hypertension (PH) is not only a hemodynamic phenomenon but also a complex syndrome involving abnormal fat tissue distribution, over-activity of the sympathetic nervous system (SNS), metabolic abnormalities, and activation of the immune system. In children, PH usually presents with a typical phenotype of disturbed body composition, accelerated biological maturity, and subtle immunological and metabolic abnormalities. This stage of the disease is potentially reversible. However, long-lasting over-activity of the SNS and immuno-metabolic alterations usually lead to an irreversible stage of cardiovascular disease. We describe an intermediate phenotype of children with PH, showing that PH is associated with accelerated development, i.e., early premature aging of the immune, metabolic, and vascular systems. The associations and determinants of hypertensive organ damage, the principles of treatment, and the possibility of rejuvenation of the cardiovascular system are discussed. Twit Text FOAVip Primary hypertension is a disease of premature vascular aging associated with neuro-immuno-metabolic abnormalities ????Pediatr Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=25724169 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25724169 #FOAvip English Wikipedia <ref>{{Cite pmid|25724169 }}</ref> Primary hypertension is a disease of premature vascular aging associated with neuro-immuno-metabolic abnormalities #MMPMID25724169 Litwin M ; Feber J ; Niemirska A ; Micha?kiewicz J Pediatr Nephrol 2016[Feb]; 31 (2 ): 185-94 PMID25724169 show ga There is an increasing amount of data indicating that primary hypertension (PH) is not only a hemodynamic phenomenon but also a complex syndrome involving abnormal fat tissue distribution, over-activity of the sympathetic nervous system (SNS), metabolic abnormalities, and activation of the immune system. In children, PH usually presents with a typical phenotype of disturbed body composition, accelerated biological maturity, and subtle immunological and metabolic abnormalities. This stage of the disease is potentially reversible. However, long-lasting over-activity of the SNS and immuno-metabolic alterations usually lead to an irreversible stage of cardiovascular disease. We describe an intermediate phenotype of children with PH, showing that PH is associated with accelerated development, i.e., early premature aging of the immune, metabolic, and vascular systems. The associations and determinants of hypertensive organ damage, the principles of treatment, and the possibility of rejuvenation of the cardiovascular system are discussed. |Aging, Premature/complications/*physiopathology [MESH] |Body Composition [MESH] |Child [MESH] |Essential Hypertension [MESH] |Hemodynamics [MESH] |Humans [MESH] |Hypertension/immunology/*physiopathology [MESH] |Metabolic Syndrome/complications [MESH] |Obesity/complications [MESH]Primary hypertension is a disease of premature vascular aging associat(epmc).pdf DeepDyve Pubget Overpricing