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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Anesth+Pain+Med
2015 ; 5
(6
): e30643
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English Wikipedia
Magnesium Versus Bupivacaine Infiltration in Controlling Postoperative Pain in
Inguinal Hernia Repair
#MMPMID26705525
Razavi SS
; Peyvandi H
; Badrkhani Jam AR
; Safari F
; Teymourian H
; Mohajerani SA
Anesth Pain Med
2015[Dec]; 5
(6
): e30643
PMID26705525
show ga
BACKGROUND: Postoperative pain is one of the most common problems after hernia
repair. Decrease in postoperative pain accelerates functional recovery, decreases
duration of hospital stay and postoperative morbidity. OBJECTIVES: To compare
postoperative analgesic effect of infiltration of magnesium versus bupivacaine
into incision of inguinal hernia repair. PATIENTS AND METHODS: In a double blind
clinical trial, 80 patients' candidates for elective inguinal hernia repair were
enrolled. Right before closure of incision, in Bupivacaine group 5 mL Bupivacaine
0.5% added to 5 mL normal saline and in Magnesium group, 10 mL Magnesium sulfate
20% was infused subcutaneously. Pain score was measured using numeric rating
score (NRS) at 1, 3, 6, 12 and 24 hours postoperatively. If NRS was above 3, 1 mg
morphine was administered as rescue analgesic until patient felt comfortable or
NRS < 3. RESULTS: Postoperative pain scores at 1 and 3 hours were not
significantly different between bupivacaine and magnesium groups (P = 0.21,
0.224; respectively). However, at 6 (P = 0.003), 12 (P = 0.028) and 24 (P =
0.022) hours postoperative, pain score (NRS) was significantly lower in
bupivacaine group. Number of patients needed at least 1 dose of rescue morphine
(P = 0.001), mean number of episodes asked for morphine during next 24 hours (P =
0.001) and total dose of morphine requirement (P = 0.01) were significantly lower
in bupivacaine group. CONCLUSIONS: Magnesium infiltration did not decrease total
dose and number of episodes needed for morphine rescue analgesic. Bupivacaine
infiltration into surgical site was more effective than magnesium sulfate
infiltration in postoperative pain control.