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10.1038/ni.3294 http://scihub22266oqcxt.onion/10.1038/ni.3294 C4685755!4685755!26523868     free     free     free Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nat+Immunol 2016 ; 17 (1): 57-64 Nephropedia Template TP {{tp|p=26523868|t=2016. Group 2 innate lymphoid cells license dendritic cells to potentiate memory T helper 2 cell responses |pdf=|usr=}}{{26523868}} gab.com Text Group 2 innate lymphoid cells license dendritic cells to potentiate memory T helper 2 cell responses JO: Nat Immunol http://www.kidney.de/pget.php?&tw=1&pmid=26523868 #FOAvip Rapid memory CD4+ T helper 2 (TH2) cell activation during allergic inflammation requires their recruitment into the affected tissue. Here we demonstrate that group 2 innate lymphoid cells (ILC2) play a critical role in memory TH2 cell responses, with targeted ILC2 depletion profoundly impairing TH2 cell localization to the lungs and skin of sensitized mice after allergen re-challenge. ILC2-derived interleukin-13 (IL-13) is critical for eliciting IRF4+CD11b+CD103? dendritic cells (DCs) to produce the TH2 cell-attracting chemokine CCL17. Consequently, the sentinel function of DCs is contingent on ILC2s for the generation of an efficient memory TH2 cell response. These results elucidate a key new innate mechanism in the regulation of the immune memory response to allergens. Twit Text FOAVip Group 2 innate lymphoid cells license dendritic cells to potentiate memory T helper 2 cell responses ????Nat Immunol http://www.kidney.de/pget.php?&tw=1&pmid=26523868 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26523868 #FOAvip English Wikipedia <ref>{{Cite pmid|26523868}}</ref> Group 2 innate lymphoid cells license dendritic cells to potentiate memory T helper 2 cell responses #MMPMID26523868 Halim TY; Hwang YY; Scanlon ST; Zaghouani H; Garbi N; Fallon PG; McKenzie AN Nat Immunol 2016[Jan]; 17 (1): 57-64 PMID26523868show ga Rapid memory CD4+ T helper 2 (TH2) cell activation during allergic inflammation requires their recruitment into the affected tissue. Here we demonstrate that group 2 innate lymphoid cells (ILC2) play a critical role in memory TH2 cell responses, with targeted ILC2 depletion profoundly impairing TH2 cell localization to the lungs and skin of sensitized mice after allergen re-challenge. ILC2-derived interleukin-13 (IL-13) is critical for eliciting IRF4+CD11b+CD103? dendritic cells (DCs) to produce the TH2 cell-attracting chemokine CCL17. Consequently, the sentinel function of DCs is contingent on ILC2s for the generation of an efficient memory TH2 cell response. These results elucidate a key new innate mechanism in the regulation of the immune memory response to allergens. äGroup 2 innate lymphoid cells license dendritic cells to potentiate me(epmc).pdf DeepDyve Pubget Overpricing