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10.4103/0972-2327.165454 http://scihub22266oqcxt.onion/10.4103/0972-2327.165454 C4683878!4683878!26713011     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Ann+Indian+Acad+Neurol 2015 ; 18 (4): 408-11 Nephropedia Template TP {{tp|p=26713011|t=2015. Autoimmune encephalitis: Clinical diagnosis versus antibody confirmation |pdf=|usr=}}{{26713011}} gab.com Text Autoimmune encephalitis: Clinical diagnosis versus antibody confirmation JO: Ann Indian Acad Neurol http://www.kidney.de/pget.php?&tw=1&pmid=26713011 #FOAvip Context:: Autoimmune encephalitis is a heterogeneous disorder which is being diagnosed with increasing frequency. The diagnosis of these disorders is based on the detection of autoantibodies and characteristic clinical profiles. Aims:: We aimed to study the antibody profile in encephalitis patients with suspected autoimmune etiology presenting to a tertiary care center. Settings and Design:: The subjects were selected by screening all patients with clinical profile suggesting autoimmune encephalitis admitted in the neuromedical intensive care unit (ICU) of a tertiary care center in South India. Materials and Methods:: Patients who fulfilled modified Zuliani et al.'s, criteria for autoimmune encephalitis were identified during the period December 2009?June 2013. Blood samples from these subjects were screened for six neuronal antibodies. Statistical analysis used:: Chi-square test was applied to compare the antibody positive and negative patients. Results:: Out of 1,227 patients screened, 39 subjects (14 males: 25 females) were identified with a mean age of 15.95 years and 19 cases were assessed in the acute and 20 in the convalescent phase of the illness. Seizure (87.8 %) was the most common presenting symptom; status epilepticus occurred in 23 (60.5%) patients during the course of the illness. Fourteen (35.9%) patients were N-methyl-D-aspartate receptor (NMDAR) antibody-positive and all were negative for the other antibodies tested. Conclusions:: One-third of patients presenting with acute noninfective encephalitis would be positive for NMDAR antibodies with the remaining two-thirds with clinically suspected autoimmune encephalitis being antibody-negative. There are few markers in the clinical and investigative profiles to distinguish antibody-positive and -negative patients. Twit Text FOAVip Autoimmune encephalitis: Clinical diagnosis versus antibody confirmation ????Ann Indian Acad Neurol http://www.kidney.de/pget.php?&tw=1&pmid=26713011 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26713011 #FOAvip English Wikipedia <ref>{{Cite pmid|26713011}}</ref> Autoimmune encephalitis: Clinical diagnosis versus antibody confirmation #MMPMID26713011 Cyril AC; Nair SS; Mathai A; Kannoth S; Thomas SV Ann Indian Acad Neurol 2015[Oct]; 18 (4): 408-11 PMID26713011show ga Context:: Autoimmune encephalitis is a heterogeneous disorder which is being diagnosed with increasing frequency. The diagnosis of these disorders is based on the detection of autoantibodies and characteristic clinical profiles. Aims:: We aimed to study the antibody profile in encephalitis patients with suspected autoimmune etiology presenting to a tertiary care center. Settings and Design:: The subjects were selected by screening all patients with clinical profile suggesting autoimmune encephalitis admitted in the neuromedical intensive care unit (ICU) of a tertiary care center in South India. Materials and Methods:: Patients who fulfilled modified Zuliani et al.'s, criteria for autoimmune encephalitis were identified during the period December 2009?June 2013. Blood samples from these subjects were screened for six neuronal antibodies. Statistical analysis used:: Chi-square test was applied to compare the antibody positive and negative patients. Results:: Out of 1,227 patients screened, 39 subjects (14 males: 25 females) were identified with a mean age of 15.95 years and 19 cases were assessed in the acute and 20 in the convalescent phase of the illness. Seizure (87.8 %) was the most common presenting symptom; status epilepticus occurred in 23 (60.5%) patients during the course of the illness. Fourteen (35.9%) patients were N-methyl-D-aspartate receptor (NMDAR) antibody-positive and all were negative for the other antibodies tested. Conclusions:: One-third of patients presenting with acute noninfective encephalitis would be positive for NMDAR antibodies with the remaining two-thirds with clinically suspected autoimmune encephalitis being antibody-negative. There are few markers in the clinical and investigative profiles to distinguish antibody-positive and -negative patients. äAutoimmune encephalitis: Clinical diagnosis versus antibody confirmati(epmc).pdf DeepDyve Pubget Overpricing