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2015 ; 3
(6
): E642-5
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
A novel colonoscope with panoramic visualization detected more simulated polyps
than conventional colonoscopy in a live swine model
#MMPMID26716128
Gluck N
; Fishman S
; Melhem A
; Goldfarb S
; Halpern Z
; Santo E
Endosc Int Open
2015[Dec]; 3
(6
): E642-5
PMID26716128
show ga
BACKGROUND AND STUDY AIMS: The Aer-O-Scope? Colonoscope System (AOS) combines
panoramic 360° view with standard forward view. We assessed the AOS's ability to
identify lesions implanted in live swine, compared to conventional colonoscopy
(CC). PATIENTS AND METHODS: Twelve swine colons were surgically ligated and beads
sewn within. Five procedures (3 AOS and 2 CC) were performed on each swine and
findings reported. Physicians were blinded to number, size, and color of beads.
The sequence of procedures and physicians was randomized. Pigs, physicians, and
colonoscopes were randomly alternated between examination rooms, maintaining
physician blindness. Two independent blinded physicians interpreted procedure
videos offline. RESULTS: A total of 259?/273 (94.9?%) of lesions were visualized
by AOS compared to 158?/182 with CC (86.8?%) (P?=?0.002). Miss rates of lesions
??6?mm were 2.6?% and 10.5?%, respectively (P?=?0.022), and 6.9?% and 15.1?%,
respectively, for lesions?6?mm (P?=?0.031). Mean agreement between AOS and CC
for lesion detection was 88.3?%. The benefit of AOS was maintained in offline
video review. CONCLUSIONS: AOS, featuring panoramic 360° view, demonstrated high
detection rates for simulated colonic lesions in a live swine model.