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10.1055/s-0034-1392771

http://scihub22266oqcxt.onion/10.1055/s-0034-1392771
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C4683134!4683134!26716127
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suck abstract from ncbi


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pmid26716127      Endosc+Int+Open 2015 ; 3 (6): E636-41
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  • Mechanisms of hyoscine butylbromide to improve adenoma detection: A case-control study of surface visualization at simulated colonoscope withdrawal #MMPMID26716127
  • East JE; Saunders BP; Burling D; Tam E; Boone D; Halligan S; Taylor SA
  • Endosc Int Open 2015[Dec]; 3 (6): E636-41 PMID26716127show ga
  • Background and study aims: Antispasmodics may improve mucosal visualization during colonoscope withdrawal, potentially improving polyp and adenoma detection. Meta-analysis and case-control studies suggest a 9?% to 13?% relative increase in adenoma and polyp detection. We aimed to assess the impact of hyoscine butylbromide on the expected visualization during colonoscope withdrawal using a CT colonography (CTC) simulation.Patients and methods: Datasets from a previous CTC study examining the effect of antispasmodic were re-analyzed with customised CTC software, adjusted to simulate a standard colonoscopic view. Eighty-six patients received intravenous (IV) hyoscine butylbromide 20?mg, 40?mg or no antispasmodic. Main outcome measurements at unidirectional flythrough, simulating colonoscope withdrawal, were percentage colonic surface visualization, numbers and sizes of unseen areas, and colonic length.Results: Use of antispasmodic was associated with a significant relative increase in percentage surface visualization of 2.6?% to 3.9?%, compared with no antispasmodic, P?
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