Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1371/journal.pcbi.1004608 http://scihub22266oqcxt.onion/10.1371/journal.pcbi.1004608 C4682976!4682976 !26680762     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26680762 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       PLoS+Comput+Biol 2015 ; 11 (12 ): e1004608 Nephropedia Template TP {{tp|p=26680762 |t=2015. Dynamic Network Drivers of Seizure Generation, Propagation and Termination in Human Neocortical Epilepsy |pdf=|usr=}}{{26680762 }} gab.com Text Dynamic Network Drivers of Seizure Generation, Propagation and Termination in Human Neocortical Epilepsy JO: PLoS Comput Biol http://www.kidney.de/pget.php?&tw=1&pmid=26680762 #FOAvip The epileptic network is characterized by pathologic, seizure-generating 'foci' embedded in a web of structural and functional connections. Clinically, seizure foci are considered optimal targets for surgery. However, poor surgical outcome suggests a complex relationship between foci and the surrounding network that drives seizure dynamics. We developed a novel technique to objectively track seizure states from dynamic functional networks constructed from intracranial recordings. Each dynamical state captures unique patterns of network connections that indicate synchronized and desynchronized hubs of neural populations. Our approach suggests that seizures are generated when synchronous relationships near foci work in tandem with rapidly changing desynchronous relationships from the surrounding epileptic network. As seizures progress, topographical and geometrical changes in network connectivity strengthen and tighten synchronous connectivity near foci-a mechanism that may aid seizure termination. Collectively, our observations implicate distributed cortical structures in seizure generation, propagation and termination, and may have practical significance in determining which circuits to modulate with implantable devices. Twit Text FOAVip Dynamic Network Drivers of Seizure Generation, Propagation and Termination in Human Neocortical Epilepsy ????PLoS Comput Biol http://www.kidney.de/pget.php?&tw=1&pmid=26680762 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26680762 #FOAvip English Wikipedia <ref>{{Cite pmid|26680762 }}</ref> Dynamic Network Drivers of Seizure Generation, Propagation and Termination in Human Neocortical Epilepsy #MMPMID26680762 Khambhati AN ; Davis KA ; Oommen BS ; Chen SH ; Lucas TH ; Litt B ; Bassett DS PLoS Comput Biol 2015[Dec]; 11 (12 ): e1004608 PMID26680762 show ga The epileptic network is characterized by pathologic, seizure-generating 'foci' embedded in a web of structural and functional connections. Clinically, seizure foci are considered optimal targets for surgery. However, poor surgical outcome suggests a complex relationship between foci and the surrounding network that drives seizure dynamics. We developed a novel technique to objectively track seizure states from dynamic functional networks constructed from intracranial recordings. Each dynamical state captures unique patterns of network connections that indicate synchronized and desynchronized hubs of neural populations. Our approach suggests that seizures are generated when synchronous relationships near foci work in tandem with rapidly changing desynchronous relationships from the surrounding epileptic network. As seizures progress, topographical and geometrical changes in network connectivity strengthen and tighten synchronous connectivity near foci-a mechanism that may aid seizure termination. Collectively, our observations implicate distributed cortical structures in seizure generation, propagation and termination, and may have practical significance in determining which circuits to modulate with implantable devices. |*Models, Neurological [MESH] |*Synaptic Transmission [MESH] |Action Potentials [MESH] |Computer Simulation [MESH] |Epilepsy/*physiopathology [MESH] |Humans [MESH] |Neocortex/*physiopathology [MESH] |Nerve Net/*physiopathology [MESH] |Neural Inhibition [MESH]Dynamic Network Drivers of Seizure Generation, Propagation and Termina(epmc).pdf DeepDyve Pubget Overpricing