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10.1002/eji.201546035 http://scihub22266oqcxt.onion/10.1002/eji.201546035 C4682349!4682349!26444855     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Eur+J+Immunol 2015 ; 45 (11): 2998-3001 Nephropedia Template TP {{tp|p=26444855|t=2015. Enhancing our understanding of enhancers in T helper cells |pdf=|usr=}}{{26444855}} gab.com Text Enhancing our understanding of enhancers in T helper cells JO: Eur J Immunol http://www.kidney.de/pget.php?&tw=1&pmid=26444855 #FOAvip A long-standing question in immunology has been to understand how transcription factors determine cell-type-specific transcription programs. Traditionally, investigating transcription factors in immune cells has been limited to measuring the effect of a single transcription factor on a limited number of gene targets. The advent of next generation sequencing methods makes it possible to measure the effects of multiple transcription factors on a genome-wide scale. This holistic approach gives us a better understanding of the influence that multiple transcription factors have on cell-specific programs. In this issue of European Journal of Immunology, Fang et al. [Eur. J. Immunol. 2015. 45: XXXX-XXXX] show that genomic regions co-occupied with two or more transcription factors show increased epigenetic histone marks of active enhancers, which correspond to increased transcriptional activity. Twit Text FOAVip Enhancing our understanding of enhancers in T helper cells ????Eur J Immunol http://www.kidney.de/pget.php?&tw=1&pmid=26444855 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26444855 #FOAvip English Wikipedia <ref>{{Cite pmid|26444855}}</ref> Enhancing our understanding of enhancers in T helper cells #MMPMID26444855 Paiano JJ; Johnson JL; Vahedi G Eur J Immunol 2015[Nov]; 45 (11): 2998-3001 PMID26444855show ga A long-standing question in immunology has been to understand how transcription factors determine cell-type-specific transcription programs. Traditionally, investigating transcription factors in immune cells has been limited to measuring the effect of a single transcription factor on a limited number of gene targets. The advent of next generation sequencing methods makes it possible to measure the effects of multiple transcription factors on a genome-wide scale. This holistic approach gives us a better understanding of the influence that multiple transcription factors have on cell-specific programs. In this issue of European Journal of Immunology, Fang et al. [Eur. J. Immunol. 2015. 45: XXXX-XXXX] show that genomic regions co-occupied with two or more transcription factors show increased epigenetic histone marks of active enhancers, which correspond to increased transcriptional activity. äEnhancing our understanding of enhancers in T helper cells (epmc).pdf DeepDyve Pubget Overpricing