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10.1038/srep18303 http://scihub22266oqcxt.onion/10.1038/srep18303 C4682136!4682136!26673905     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2015 ; 5 (ä): ä Nephropedia Template TP {{tp|p=26673905|t=2015. Development of a real-time flexible multiphoton microendoscope for label-free imaging in a live animal |pdf=|usr=}}{{26673905}} gab.com Text Development of a real-time flexible multiphoton microendoscope for label-free imaging in a live animal JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=26673905 #FOAvip We present a two-photon microendoscope capable of in vivo label-free deep-tissue high-resolution fast imaging through a very long optical fiber. First, an advanced light-pulse spectro-temporal shaping device optimally precompensates for linear and nonlinear distortions occurring during propagation within the endoscopic fiber. This enables the delivery of sub-40-fs duration infrared excitation pulses at the output of 5?meters of fiber. Second, the endoscopic fiber is a custom-made double-clad polarization-maintaining photonic crystal fiber specifically designed to optimize the imaging resolution and the intrinsic luminescence backward collection. Third, a miniaturized fiber-scanner of 2.2?mm outer diameter allows simultaneous second harmonic generation (SHG) and two-photon excited autofluorescence (TPEF) imaging at 8 frames per second. This microendoscope?s transverse and axial resolutions amount respectively to 0.8??m and 12??m, with a field-of-view as large as 450??m. This microendoscope?s unprecedented capabilities are validated during label-free imaging, ex vivo on various fixed human tissue samples, and in vivo on an anesthetized mouse kidney demonstrating an imaging penetration depth greater than 300??m below the surface of the organ. The results reported in this manuscript confirm that nonlinear microendoscopy can become a valuable clinical tool for real-time in situ assessment of pathological states. Twit Text FOAVip Development of a real-time flexible multiphoton microendoscope for label-free imaging in a live animal ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=26673905 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26673905 #FOAvip English Wikipedia <ref>{{Cite pmid|26673905}}</ref> Development of a real-time flexible multiphoton microendoscope for label-free imaging in a live animal #MMPMID26673905 Ducourthial G; Leclerc P; Mansuryan T; Fabert M; Brevier J; Habert R; Braud F; Batrin R; Vever-Bizet C; Bourg-Heckly G; Thiberville L; Druilhe A; Kudlinski A; Louradour F Sci Rep 2015[]; 5 (ä): ä PMID26673905show ga We present a two-photon microendoscope capable of in vivo label-free deep-tissue high-resolution fast imaging through a very long optical fiber. First, an advanced light-pulse spectro-temporal shaping device optimally precompensates for linear and nonlinear distortions occurring during propagation within the endoscopic fiber. This enables the delivery of sub-40-fs duration infrared excitation pulses at the output of 5?meters of fiber. Second, the endoscopic fiber is a custom-made double-clad polarization-maintaining photonic crystal fiber specifically designed to optimize the imaging resolution and the intrinsic luminescence backward collection. Third, a miniaturized fiber-scanner of 2.2?mm outer diameter allows simultaneous second harmonic generation (SHG) and two-photon excited autofluorescence (TPEF) imaging at 8 frames per second. This microendoscope?s transverse and axial resolutions amount respectively to 0.8??m and 12??m, with a field-of-view as large as 450??m. This microendoscope?s unprecedented capabilities are validated during label-free imaging, ex vivo on various fixed human tissue samples, and in vivo on an anesthetized mouse kidney demonstrating an imaging penetration depth greater than 300??m below the surface of the organ. The results reported in this manuscript confirm that nonlinear microendoscopy can become a valuable clinical tool for real-time in situ assessment of pathological states. äDevelopment of a real-time flexible multiphoton microendoscope for lab(epmc).pdf DeepDyve Pubget Overpricing