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10.1186/s13613-015-0090-8 http://scihub22266oqcxt.onion/10.1186/s13613-015-0090-8 C4681181!4681181!26667819     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26667819&cmd=llinks): Failed to open stream: HTTP request failed! 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Screening of patients with augmented renal clearance in ICU: taking into account the CKD-EPI equation, the age, and the cause of admission |pdf=|usr=}}{{26667819}} gab.com Text Screening of patients with augmented renal clearance in ICU: taking into account the CKD-EPI equation, the age, and the cause of admission JO: Ann Intensive Care http://www.kidney.de/pget.php?&tw=1&pmid=26667819 #FOAvip Background: In ICU patients with normal serum creatinine (SCr), a state of increased renal drug excretion has been described (creatinine clearance ?130 ml/min/1.73 m2), and named augmented renal clearance (ARC). In ICU patients, the accuracy of GFR estimates is insufficient. However, in clinical practice, the physician has not at one?s disposal patient measured creatinine clearance (CrCl) when prescribing. The primary objective of this study was to assess the accuracy of 4 formulas to estimate GFR (Cockcroft-Gault (CG), Robert, sMDRD, and CKD-EPI formulas) with other covariates to detect ARC in ICU patients. Methods: We enroled 360 consecutive ICU patients with normal SCr in this prospective observational study conducted in a primary teaching hospital. Comparisons between CrCl values and 4 estimated GFR (eGFR) formulas were estimated. Results: In these 360 patients, ARC was observed in 33 % of patients most of them trauma. Individual predictive values of equations were poor and the phenomenon increased in ARC subgroup. CG and CKD-EPI were more accurate to detect an ARC. Multivariable analysis showed that the best-fitting model included 3 factors independently correlated to ARC: trauma patients, cut-off values of age ?58 years, and CKD-EPI more than 108 ml/min/1.73 m2. Conclusions: In ICU patients with normal SCr, eGFR formulas are imprecise in assessing CrCl. If measured CrCl must be ideally used to detect modifications of the renal function, in clinical practice, age, reason for admission, and CKD-EPI could be used as screening tool to identify ARC. Twit Text FOAVip Screening of patients with augmented renal clearance in ICU: taking into account the CKD-EPI equation, the age, and the cause of admission ????Ann Intensive Care http://www.kidney.de/pget.php?&tw=1&pmid=26667819 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26667819 #FOAvip English Wikipedia <ref>{{Cite pmid|26667819}}</ref> Screening of patients with augmented renal clearance in ICU: taking into account the CKD-EPI equation, the age, and the cause of admission #MMPMID26667819 Ruiz S; Minville V; Asehnoune K; Virtos M; Georges B; Fourcade O; Conil JM Ann Intensive Care 2015[]; 5 (ä): ä PMID26667819show ga Background: In ICU patients with normal serum creatinine (SCr), a state of increased renal drug excretion has been described (creatinine clearance ?130 ml/min/1.73 m2), and named augmented renal clearance (ARC). In ICU patients, the accuracy of GFR estimates is insufficient. However, in clinical practice, the physician has not at one?s disposal patient measured creatinine clearance (CrCl) when prescribing. The primary objective of this study was to assess the accuracy of 4 formulas to estimate GFR (Cockcroft-Gault (CG), Robert, sMDRD, and CKD-EPI formulas) with other covariates to detect ARC in ICU patients. Methods: We enroled 360 consecutive ICU patients with normal SCr in this prospective observational study conducted in a primary teaching hospital. Comparisons between CrCl values and 4 estimated GFR (eGFR) formulas were estimated. Results: In these 360 patients, ARC was observed in 33 % of patients most of them trauma. Individual predictive values of equations were poor and the phenomenon increased in ARC subgroup. CG and CKD-EPI were more accurate to detect an ARC. Multivariable analysis showed that the best-fitting model included 3 factors independently correlated to ARC: trauma patients, cut-off values of age ?58 years, and CKD-EPI more than 108 ml/min/1.73 m2. Conclusions: In ICU patients with normal SCr, eGFR formulas are imprecise in assessing CrCl. If measured CrCl must be ideally used to detect modifications of the renal function, in clinical practice, age, reason for admission, and CKD-EPI could be used as screening tool to identify ARC. äScreening of patients with augmented renal clearance in ICU: taking in(epmc).pdf DeepDyve Pubget Overpricing