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10.1099/vir.0.000151 http://scihub22266oqcxt.onion/10.1099/vir.0.000151 C4681073!4681073!25888622     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Gen+Virol 2015 ; 96 (Pt 8): 2464-9 Nephropedia Template TP {{tp|p=25888622|t=2015. The placenta shed from goats with classical scrapie is infectious to goat kids and lambs |pdf=|usr=}}{{25888622}} gab.com Text The placenta shed from goats with classical scrapie is infectious to goat kids and lambs JO: J Gen Virol http://www.kidney.de/pget.php?&tw=1&pmid=25888622 #FOAvip The placenta of domestic sheep plays a key role in horizontal transmission of classical scrapie. Domestic goats are frequently raised with sheep and are susceptible to classical scrapie, yet potential routes of transmission from goats to sheep are not fully defined. Sparse accumulation of disease-associated prion protein in cotyledons casts doubt about the role of the goat's placenta. Thus, relevant to mixed-herd management and scrapie-eradication efforts worldwide, we determined if the goat's placenta contains prions orally infectious to goat kids and lambs. A pooled cotyledon homogenate, prepared from the shed placenta of a goat with naturally acquired classical scrapie disease, was used to orally inoculate scrapie-na?¨ve prion genotype-matched goat kids and scrapie-susceptible lambs raised separately in a scrapie-free environment. Transmission was detected in all four goats and in two of four sheep, which importantly identifies the goat's placenta as a risk for horizontal transmission to sheep and other goats. Twit Text FOAVip The placenta shed from goats with classical scrapie is infectious to goat kids and lambs ????J Gen Virol http://www.kidney.de/pget.php?&tw=1&pmid=25888622 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25888622 #FOAvip English Wikipedia <ref>{{Cite pmid|25888622}}</ref> The placenta shed from goats with classical scrapie is infectious to goat kids and lambs #MMPMID25888622 Schneider DA; Madsen-Bouterse SA; Zhuang D; Truscott TC; Dassanayake RP; O'Rourke KI J Gen Virol 2015[Aug]; 96 (Pt 8): 2464-9 PMID25888622show ga The placenta of domestic sheep plays a key role in horizontal transmission of classical scrapie. Domestic goats are frequently raised with sheep and are susceptible to classical scrapie, yet potential routes of transmission from goats to sheep are not fully defined. Sparse accumulation of disease-associated prion protein in cotyledons casts doubt about the role of the goat's placenta. Thus, relevant to mixed-herd management and scrapie-eradication efforts worldwide, we determined if the goat's placenta contains prions orally infectious to goat kids and lambs. A pooled cotyledon homogenate, prepared from the shed placenta of a goat with naturally acquired classical scrapie disease, was used to orally inoculate scrapie-na?¨ve prion genotype-matched goat kids and scrapie-susceptible lambs raised separately in a scrapie-free environment. Transmission was detected in all four goats and in two of four sheep, which importantly identifies the goat's placenta as a risk for horizontal transmission to sheep and other goats. äThe placenta shed from goats with classical scrapie is infectious to g(epmc).pdf DeepDyve Pubget Overpricing