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10.1038/nrn3983 http://scihub22266oqcxt.onion/10.1038/nrn3983 C4678594!4678594!26243569     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nat+Rev+Neurosci 2015 ; 16 (9): 564-74 Nephropedia Template TP {{tp|p=26243569|t=2015. A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome |pdf=|usr=}}{{26243569}} gab.com Text A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome JO: Nat Rev Neurosci http://www.kidney.de/pget.php?&tw=1&pmid=26243569 #FOAvip Down syndrome, which arises in individuals carrying an extra copy of chromosome 21, is associated with a greatly increased risk of early-onset Alzheimer disease. It is thought that this risk is conferred by the presence of three copies of the gene encoding amyloid precursor protein (APP) ? an Alzheimer disease risk factor ? although the possession of extra copies of other chromosome 21 genes may also play a part. Further study of the mechanisms underlying the development of Alzheimer disease in people with Down syndrome could provide insights into the mechanisms that cause dementia in the general population. Twit Text FOAVip A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome ????Nat Rev Neurosci http://www.kidney.de/pget.php?&tw=1&pmid=26243569 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26243569 #FOAvip English Wikipedia <ref>{{Cite pmid|26243569}}</ref> A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome #MMPMID26243569 Wiseman FK; Al-Janabi T; Hardy J; Karmiloff-Smith A; Nizetic D; Tybulewicz VLJ; Fisher EMC; Strydom A Nat Rev Neurosci 2015[Sep]; 16 (9): 564-74 PMID26243569show ga Down syndrome, which arises in individuals carrying an extra copy of chromosome 21, is associated with a greatly increased risk of early-onset Alzheimer disease. It is thought that this risk is conferred by the presence of three copies of the gene encoding amyloid precursor protein (APP) ? an Alzheimer disease risk factor ? although the possession of extra copies of other chromosome 21 genes may also play a part. Further study of the mechanisms underlying the development of Alzheimer disease in people with Down syndrome could provide insights into the mechanisms that cause dementia in the general population. äA genetic cause of Alzheimer disease: mechanistic insights from Down s(epmc).pdf DeepDyve Pubget Overpricing