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10.1038/ncb2769

http://scihub22266oqcxt.onion/10.1038/ncb2769
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C4678324!4678324!23728460
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suck abstract from ncbi


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pmid23728460      Nat+Cell+Biol 2013 ; 15 (6): 546-54
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  • Control of Metastatic Progression by microRNA Regulatory Networks #MMPMID23728460
  • Pencheva N; Tavazoie SF
  • Nat Cell Biol 2013[Jun]; 15 (6): 546-54 PMID23728460show ga
  • Aberrant microRNA (miRNA) expression is a defining feature of human malignancy. Specific miRNAs have been identified as promoters or suppressors of metastatic progression. These miRNAs control metastasis through divergent or convergent regulation of metastatic gene pathways. Some miRNA regulatory networks govern cell-autonomous cancer phenotypes, while others modulate the cell-extrinsic composition of the metastatic microenvironment. The use of small RNAs as probes into the molecular and cellular underpinnings of metastasis holds promise for the identification of candidate genes for potential therapeutic intervention.
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