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2015 ; 8
(ä): 758
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English Wikipedia
Pheochromocytoma multisystem crisis treated with emergency surgery: a case report
and literature review
#MMPMID26645353
Kakoki K
; Miyata Y
; Shida Y
; Hakariya T
; Takehara K
; Izumida S
; Sekino M
; Kinoshita N
; Igawa T
; Fukuoka J
; Sakai H
BMC Res Notes
2015[Dec]; 8
(ä): 758
PMID26645353
show ga
BACKGROUND: Pheochromocytoma is a neuroendocrine tumor that predominantly
presents with hypertension, palpitations, and tachycardia due to excessive
catecholamine excretion. Although pheochromocytoma multisystem crisis (PMC) is
relatively rare, urologists and clinicians should focus on early diagnosis as
delay in initiating the appropriate treatment can lead to mortality CASE
PRESENTATION: A 70-year-old man developed ileus after a few days of medication
for hypertension. Computed tomography incidentally revealed a left adrenal mass.
This finding together with his clinical course was compatible with
pheochromocytoma. An ?-blocker was administered immediately, and his blood
pressure was well controlled. However, his general condition and laboratory data
deteriorated rapidly, and the patient was diagnosed with PMC with lethal status.
Thus, emergency adrenalectomy was performed without confirmation of catecholamine
levels. From the resected specimen, his tumor was judged as pheochromocytoma. On
immunohistochemical analysis, the proliferation index evaluated by Ki-67 staining
was 9.7 %. This case report was approved by the Human Ethics Review Committee of
the Nagasaki University Hospital. CONCLUSION: The present case of PMC was
successfully treated with emergency surgery. The benign pheochromocytoma also
presented with high cell proliferation potential, which may be a cause of the
extreme aggressiveness of PMC.
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