Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25774007
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Expert+Rev+Mol+Diagn
2015 ; 15
(5
): 617-29
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Biomarker development for presymptomatic molecular diagnosis of preeclampsia:
feasible, useful or even unnecessary?
#MMPMID25774007
Hahn S
; Lapaire O
; Than NG
Expert Rev Mol Diagn
2015[May]; 15
(5
): 617-29
PMID25774007
show ga
The past decade saw the advent of a number of promising biomarkers to detect
pregnancies at risk for preeclampsia (PE), the foremost being those associated
with an imbalance of angiogenic factors. In late pregnancy, these are useful for
the detection of imminent cases of PE, while earlier they were more predictive
for early- than late-onset PE. This suggests that there may be fundamental
differences between the underlying pathology of these two PE forms. Therefore, it
is possible that such a biological premise may limit the development of
biomarkers that will permit the efficacious detection of both early- and
late-onset PE via an analysis of first-trimester maternal blood samples.
Consequently, a significant increase in our understanding of the underlying
pathology of PE, using a variety of approaches ranging from systems biology to
animal models, will be necessary in order to overcome this obstacle.