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2015 ; 10
(12
): e0140207
Nephropedia Template TP
gab.com Text
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English Wikipedia
Coping with Space Neophobia in Drosophila melanogaster: The Asymmetric Dynamics
of Crossing a Doorway to the Untrodden
#MMPMID26646394
Cohen S
; Benjamini Y
; Golani I
PLoS One
2015[]; 10
(12
): e0140207
PMID26646394
show ga
We discover and examine within a wide phylogenetic perspective spatial neophobia,
avoidance of untrodden terrain, in fruit flies, in an experimental setup that
reduces the gap between the field and the laboratory. In our setup, fruit flies
use a natal fruit as their origin, freely exploring for days their surroundings,
which consists of a mixture of trodden and untrodden terrain. The interface
between trodden and untrodden is, however, reduced in our setup to a wide
doorway, opened within a surrounding wall. Crossing this doorway, characterized
by a sharp contrast interface between trodden and untrodden, generates a behavior
whose dynamics betrays the flies' space neophobia. The moment-by-moment dynamics
of crossing is remarkably similar to that reported in mouse models of anxiety.
This means that neophobic behavior is either homologous across arthropods and
vertebrates or, not less interesting, convergent, whereby the same behavior is
mediated in the two phyla by two completely different schemata.