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10.1038/srep17462

http://scihub22266oqcxt.onion/10.1038/srep17462
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C4672335!4672335!26642822
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suck abstract from ncbi


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pmid26642822      Sci+Rep 2015 ; 5 (ä): ä
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  • Detection of airborne viruses using electro-aerodynamic deposition and a field-effect transistor #MMPMID26642822
  • Park KT; Cho DG; Park JW; Hong S; Hwang J
  • Sci Rep 2015[]; 5 (ä): ä PMID26642822show ga
  • We report a technique for the detection of aerosolized viruses. Conventional field-effect-transistor (FET)-based techniques use solution-based processes, thus require antibody binding to the detection region of the FET prior to the supply of the analyte. With the method described here, virus?antibody-bound particles are delivered to the FET during detection; therefore, neither a pre-treatment antibody binding step on the FET channel nor washing process for virus?antibody-binding are necessary. Our method is based on the concept that virus?antibody-bound particles are larger than the virus or antibody alone, and thus have larger charge numbers following aerosol charging. When these particles are charged by negative ions and electro-aerodynamically deposited on a substrate, there exists a location on the substrate where neither lone virus nor antibody particles land, and where only virus?antibody-bound particles are deposited. If this location coincides with the channel of the FET, the resulting variation in the current can be used to indicate the existence of a virus. By aerosolizing a mixed solution of the virus and the antibody, only the virus?antibody-bound particles were transported to the swCNT-FET, and the electric current in the swCNT-FET decreased to 30% of that measured with no deposited particles.
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