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10.1038/srep17921

http://scihub22266oqcxt.onion/10.1038/srep17921
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C4672306!4672306!26643589
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suck abstract from ncbi


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pmid26643589      Sci+Rep 2015 ; 5 (ä): ä
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  • Vitamin C intake and risk of renal cell carcinoma: a meta-analysis #MMPMID26643589
  • Jia L; Jia Q; Shang Y; Dong X; Li L
  • Sci Rep 2015[]; 5 (ä): ä PMID26643589show ga
  • Studies have showed that vitamin C intake is linked to renal cell carcinoma risk, however, the results were inconsistent. Hence, the present meta-analysis was to examine the association between vitamin C intake and RCC risk. We searched the published studies that reported the relationship between vitamin C intake and RCC risk using PubMed and Embase up to January 2015. Based on a fixed effects model, RR and the corresponding 95%?CI were used to assess the pooled risk. 3 prospective cohort studies and 7 case-control studies were included. The overall RR (95%?CI) of RCC for the highest vs. the lowest levels of vitamin C intake was 0.78(0.69,0.87). Little evidence of heterogeneity was found. In the subgroup analyses, we found an inverse association between vitamin C intake and RCC risk in the case-control studies but not in the prospective cohort studies. Additionally, this association between vitamin C intake and RCC risk was not differed by population distribution. Our study provides evidence that vitamin C intake is associated with a reduced RCC risk. However, our conclusion was just based on ten including studies, so more high-quality of case-control studies or cohort studies which report this topic are needed.
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