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http://scihub22266oqcxt.onion/ C4671797!4671797!26632791     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Am+Assoc+Lab+Anim+Sci 2015 ; 54 (6): 799-802 Nephropedia Template TP {{tp|p=26632791|t=2015. Investigation of Blue Bedding in Cages Housing Treatment-Naïve Hamsters |pdf=|usr=}}{{26632791}} gab.com Text Investigation of Blue Bedding in Cages Housing Treatment-Naïve Hamsters JO: J Am Assoc Lab Anim Sci http://www.kidney.de/pget.php?&tw=1&pmid=26632791 #FOAvip During the acclimation phase of a preclinical safety study involving Syrian golden hamsters, some of the cages of treatment-naïve animals were noted to contain blue-tinged bedding; the urine of these hamsters was not discolored. We sought to understand the underlying cause of this unusual finding to ensure that the study animals were healthy and free from factors that might confound the interpretation of the study. Analysis of extracts from the blue bedding by using HPLC with inline UV detection and high-resolution mass spectrometry indicated that the color was due to the presence of indigo blue. Furthermore, the indigo blue likely was formed through a series of biochemical events initiated by the intestinal metabolism of tryptophan to an indoxyl metabolite. We offer 2 hypotheses regarding the fate of the indoxyl metabolite: indigo blue formation through oxidative coupling in the liver or through urinary bacterial metabolism. Twit Text FOAVip Investigation of Blue Bedding in Cages Housing Treatment-Naïve Hamsters ????J Am Assoc Lab Anim Sci http://www.kidney.de/pget.php?&tw=1&pmid=26632791 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26632791 #FOAvip English Wikipedia <ref>{{Cite pmid|26632791}}</ref> Investigation of Blue Bedding in Cages Housing Treatment-Naïve Hamsters #MMPMID26632791 Shah VD; Walton BJ; Culp AG; Castellino S J Am Assoc Lab Anim Sci 2015[Nov]; 54 (6): 799-802 PMID26632791show ga During the acclimation phase of a preclinical safety study involving Syrian golden hamsters, some of the cages of treatment-naïve animals were noted to contain blue-tinged bedding; the urine of these hamsters was not discolored. We sought to understand the underlying cause of this unusual finding to ensure that the study animals were healthy and free from factors that might confound the interpretation of the study. Analysis of extracts from the blue bedding by using HPLC with inline UV detection and high-resolution mass spectrometry indicated that the color was due to the presence of indigo blue. Furthermore, the indigo blue likely was formed through a series of biochemical events initiated by the intestinal metabolism of tryptophan to an indoxyl metabolite. We offer 2 hypotheses regarding the fate of the indoxyl metabolite: indigo blue formation through oxidative coupling in the liver or through urinary bacterial metabolism. äInvestigation of Blue Bedding in Cages Housing Treatment-Naïve Hamster(epmc).pdf DeepDyve Pubget Overpricing