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2015 ; 5
(ä): 17917
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The RIFLE versus AKIN classification for incidence and mortality of acute kidney
injury in critical ill patients: A meta-analysis
#MMPMID26639440
Xiong J
; Tang X
; Hu Z
; Nie L
; Wang Y
; Zhao J
Sci Rep
2015[Dec]; 5
(ä): 17917
PMID26639440
show ga
The sensitivity and accuracy of the Risk/Injury/Failure/Loss/End-stage (RIFLE)
versus acute kidney injury Network (AKIN) criteria for acute kidney injury (AKI)
in critically ill patients remains uncertain. Therefore, we performed a
systematic review and meta-analysis to investigate the incidence and prognostic
value of the RIFLE versus AKIN criteria for AKI in critically ill patients.
Literatures were identified by searching Medline, Embase, PubMed, and China
National Knowledge Infrastructure (CNKI) database. Nineteen studies with 171,889
participants were included. The pooled estimates of relative risk (RR) were
analyzed. We found that the RIFLE and AKIN criteria is different for the
incidence of AKI in intensive care unit (ICU) patients (P?=?0.02, RR?=?0.88),
while not for cardiac surgery patients (P?=?0.30, RR?=?0.93). For AKI-related
hospital mortality, the AKIN criteria did not show a better ability in predicting
hospital mortality in either ICU (P?=?0.19, RR?=?1.01) or cardiac surgery
patients (P?=?0.61, RR?=?0.98) compared to RIFLE criteria. Our findings supported
that the AKIN criteria can identify more patients in classifying AKI compared to
RIFLE criteria, but not showing a better ability in predicting hospital
mortality. Moreover, both RIFLE and AKIN criteria for AKI in cardiac surgery
patients had better predictive ability compared with the ICU patients.