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10.1016/j.trecan.2015.07.001 http://scihub22266oqcxt.onion/10.1016/j.trecan.2015.07.001 C4669894!4669894!26645049     free     free     free       Trends+Cancer 2015 ; 1 (1): 53-65 Nephropedia Template TP {{tp|p=26645049|t=2015. Targeting Transcription Factors in Cancer |pdf=|usr=}}{{26645049}} gab.com Text Targeting Transcription Factors in Cancer JO: Trends Cancer http://www.kidney.de/pget.php?&tw=1&pmid=26645049 #FOAvip Transcription factors (TFs) are commonly deregulated in the pathogenesis of human cancer and are a major class of cancer cell dependencies. Consequently, targeting of TFs can be highly effective in treating particular malignancies, as highlighted by the clinical efficacy of agents that target nuclear hormone receptors. In this review we discuss recent advances in our understanding of TFs as drug targets in oncology, with an emphasis on the emerging chemical approaches to modulate TF function. The remarkable diversity and potency of TFs as drivers of cell transformation justifies a continued pursuit of TFs as therapeutic targets for drug discovery. Twit Text FOAVip Targeting Transcription Factors in Cancer ????Trends Cancer http://www.kidney.de/pget.php?&tw=1&pmid=26645049 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26645049 #FOAvip English Wikipedia <ref>{{Cite pmid|26645049}}</ref> Targeting Transcription Factors in Cancer #MMPMID26645049 Bhagwat AS; Vakoc CR Trends Cancer 2015[Sep]; 1 (1): 53-65 PMID26645049show ga Transcription factors (TFs) are commonly deregulated in the pathogenesis of human cancer and are a major class of cancer cell dependencies. Consequently, targeting of TFs can be highly effective in treating particular malignancies, as highlighted by the clinical efficacy of agents that target nuclear hormone receptors. In this review we discuss recent advances in our understanding of TFs as drug targets in oncology, with an emphasis on the emerging chemical approaches to modulate TF function. The remarkable diversity and potency of TFs as drivers of cell transformation justifies a continued pursuit of TFs as therapeutic targets for drug discovery. äTargeting Transcription Factors in Cancer (epmc).pdf DeepDyve Pubget Overpricing